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The Effect of Exogenous Creatine Phosphate on Myocardial Injury After Percutaneous Coronary Intervention

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机构: [1]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing 100029, Peoples R China [2]Capital Med Univ, Dept Cardiol, Beijing Tongren Hosp, Beijing 100029, Peoples R China
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关键词: creatine phosphate percutaneous coronary intervention myocardial injury

摘要:
Objective: To evaluate the effect of exogenous creatine phosphate (CP) on myocardial injury after percutaneous coronary intervention (PCI). Method: Four hundred patients were divided to receive conventional therapy (control group) or 3-day intravenous infusion of CP after PCI (CP group). Levels of creatine kinase MB (CK-MB) and troponin I (TnI) were measured before and on postprocedural day 3. Results: Postprocedural CK-MB and TnI in the CP group were significantly increased compared to the control group. In the CP group, 8.0% and 5.0% of patients had an increase in CK-MB 1 to 3 times and >3 times, respectively, which were significantly lower than that of the control group (19.0% and 9.0%, respectively); 12.0% and 10.0% of patients had an increase in TnI 1 to 3 times and >3 times, respectively, which were significantly lower than that of the control group (21.0% and 18.0%, respectively). Conclusion: Exogenous CP was helpful to reduce myocardial injury after PCI.

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出版当年[2014]版:
大类 | 4 区 医学
小类 | 4 区 外周血管病
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 外周血管病
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出版当年[2013]版:
Q3 PERIPHERAL VASCULAR DISEASE
最新[2023]版:
Q2 PERIPHERAL VASCULAR DISEASE

影响因子: 最新[2023版] 最新五年平均 出版当年[2013版] 出版当年五年平均 出版前一年[2012版] 出版后一年[2014版]

第一作者:
第一作者机构: [1]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing 100029, Peoples R China [2]Capital Med Univ, Dept Cardiol, Beijing Tongren Hosp, Beijing 100029, Peoples R China
通讯作者:
通讯机构: [1]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing 100029, Peoples R China [*1]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, 12th Ward, Beijing 100029, Peoples R China
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