Background: Raised blood pressure (BP) is associated with the incidence of metabolic syndrome (MetS). It is unknown if subjects with different BP levels may develop certain components of MetS over time. We investigated the incidence of MetS relative to different levels of BP over a 5-year period in a Chinese population in Tongren Hospital, Beijing. Methods: During the period of 2006-2011, we recruited 2,781 participants with no MetS, or self-reported type 2 diabetes, dyslipidemia, hypertension, or cardiovascular disease at baseline. Association rule was used to identify the transitions of MetS components over time. Results: The incidence of MetS at follow-up was 9.74% for men and 3.21% for women in the group with optimal BP; 10.29% and 7.22%, respectively, in the group with normal BP; 10.49% and 10.84%, respectively, in the group with high-normal BP; and 14.48% and 23.21%, respectively in the group with high BP. The most common transition was from healthy to healthy in the groups with optimal or normal BP (17.9-49.3%), whereas in the high-normal BP group, 16.9-22.1% of subjects with raised BP returned to healthy status or stayed unchanged, while 13.8-21.4% of people with high BP tended to develop raised fasting glucose levels. Conclusions: The incidence of MetS increased in parallel with the increase in BP. People with optimal and normal BP levels were less susceptible to developing MetS over time, whereas abnormal BP seemed to be a pre-existing phase of MetS. High-normal BP was a crucial status for MetS prevention.
基金:
Beijing Natural Science FoundationBeijing Natural Science Foundation [7131002]; Key Projects in the National Science & Technology Pillar Program in the Twelfth Five-year Plan Period of China [2011BAI08B01]; Program of Natural Science Fund of ChinaNational Natural Science Foundation of China [81373099]; Funding Project for Beijing Municipal Natural Science Foundation [7122016]
第一作者机构:[1]Capital Med Univ, Sch Publ Hlth, Beijing 100069, Peoples R China[2]Beijing Municipal Key Lab Clin Epidemiol, Beijing 100069, Peoples R China[3]Beijing Ctr Dis Prevent & Control, Inst Infect Dis & Endem Dis Control, Beijing 100013, Peoples R China
通讯作者:
通讯机构:[1]Capital Med Univ, Sch Publ Hlth, Beijing 100069, Peoples R China[2]Beijing Municipal Key Lab Clin Epidemiol, Beijing 100069, Peoples R China
推荐引用方式(GB/T 7714):
Huo Da,Tao Lixin,Li Xia,et al.Association of blood pressure with development of metabolic syndrome components: a five-year Retrospective Cohort study in Beijing[J].BMC PUBLIC HEALTH.2013,13:doi:10.1186/1471-2458-13-912.
APA:
Huo, Da,Tao, Lixin,Li, Xia,Wang, Wei,Wang, Zhaoping...&Guo, Xiuhua.(2013).Association of blood pressure with development of metabolic syndrome components: a five-year Retrospective Cohort study in Beijing.BMC PUBLIC HEALTH,13,
MLA:
Huo, Da,et al."Association of blood pressure with development of metabolic syndrome components: a five-year Retrospective Cohort study in Beijing".BMC PUBLIC HEALTH 13.(2013)