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Association of blood pressure with development of metabolic syndrome components: a five-year Retrospective Cohort study in Beijing

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机构: [1]Capital Med Univ, Sch Publ Hlth, Beijing 100069, Peoples R China [2]Beijing Municipal Key Lab Clin Epidemiol, Beijing 100069, Peoples R China [3]Beijing Ctr Dis Prevent & Control, Inst Infect Dis & Endem Dis Control, Beijing 100013, Peoples R China [4]Natl Univ Ireland Univ Coll Cork, Dept Epidemiol & Publ Hlth, Cork, Ireland [5]Capital Inst Pediat, Dept Integrated Early Childhood Dev, Beijing 100020, Peoples R China [6]Capital Med Univ, Beijing Tongren Hosp, Phys Examinat Dept, Beijing 100730, Peoples R China
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关键词: Metabolic syndrome Blood pressure Retrospective cohort study Chinese

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Background: Raised blood pressure (BP) is associated with the incidence of metabolic syndrome (MetS). It is unknown if subjects with different BP levels may develop certain components of MetS over time. We investigated the incidence of MetS relative to different levels of BP over a 5-year period in a Chinese population in Tongren Hospital, Beijing. Methods: During the period of 2006-2011, we recruited 2,781 participants with no MetS, or self-reported type 2 diabetes, dyslipidemia, hypertension, or cardiovascular disease at baseline. Association rule was used to identify the transitions of MetS components over time. Results: The incidence of MetS at follow-up was 9.74% for men and 3.21% for women in the group with optimal BP; 10.29% and 7.22%, respectively, in the group with normal BP; 10.49% and 10.84%, respectively, in the group with high-normal BP; and 14.48% and 23.21%, respectively in the group with high BP. The most common transition was from healthy to healthy in the groups with optimal or normal BP (17.9-49.3%), whereas in the high-normal BP group, 16.9-22.1% of subjects with raised BP returned to healthy status or stayed unchanged, while 13.8-21.4% of people with high BP tended to develop raised fasting glucose levels. Conclusions: The incidence of MetS increased in parallel with the increase in BP. People with optimal and normal BP levels were less susceptible to developing MetS over time, whereas abnormal BP seemed to be a pre-existing phase of MetS. High-normal BP was a crucial status for MetS prevention.

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基金编号: 7131002 2011BAI08B01 81373099 7122016

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出版当年[2012]版:
大类 | 3 区 医学
小类 | 3 区 公共卫生、环境卫生与职业卫生
最新[2023]版:
大类 | 2 区 医学
小类 | 2 区 公共卫生、环境卫生与职业卫生
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出版当年[2011]版:
Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
最新[2023]版:
Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

影响因子: 最新[2023版] 最新五年平均 出版当年[2011版] 出版当年五年平均 出版前一年[2010版] 出版后一年[2012版]

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第一作者机构: [1]Capital Med Univ, Sch Publ Hlth, Beijing 100069, Peoples R China [2]Beijing Municipal Key Lab Clin Epidemiol, Beijing 100069, Peoples R China [3]Beijing Ctr Dis Prevent & Control, Inst Infect Dis & Endem Dis Control, Beijing 100013, Peoples R China
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通讯机构: [1]Capital Med Univ, Sch Publ Hlth, Beijing 100069, Peoples R China [2]Beijing Municipal Key Lab Clin Epidemiol, Beijing 100069, Peoples R China
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