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Flow oscillation-A measure to predict the surgery outcome for obstructed sleep apnea (OSA) subject

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收录情况： ◇ SCIE

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机构： [1]Department of Mechanical Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong [2]Affiliated Beijing Tongren Hospital, Capital Medical University, Beijing, China [3]Department of Mechanical Engineering, University of Hong Kong, Hong Kong

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关键词： Upper airway OSA Flow oscillation CFD

摘要：

Obstructed sleep apnea (OSA) is a common disorder which may need surgery to widen the airway; however the success rate of surgery is limited. Here we report a finding that could be used to predict the outcome of the OSA surgery. We found that inspiratory flow oscillates due to flow separation near the larynx, and the resulting periodic signal (3-5 Hz) is an intrinsic property of breathing. This flow oscillating signal may be the afferent stimulus to trigger respiratory events. It is found that the flow oscillation is attenuated for the OSA subjects. The computational fluid dynamics (CFD) simulation reveals that there exists flow separation near larynx and this separation is severely weakened in the OSA upper airway model. It is believed that the flow oscillating signal can serve as the measure to quantify the breathing quality of an OSA subject. This makes it possible to predict the surgery outcome of the OSA subject by applying CFD simulation. (C) 2012 Elsevier Ltd. All rights reserved.

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出版当年[2011]版：

大类 | 3 区生物

小类 | 2 区工程：生物医学 4 区生物物理

最新[2023]版：

大类 | 3 区医学

小类 | 2 区生物物理 3 区工程：生物医学

JCR分区：

出版当年[2010]版：

Q2 ENGINEERING, BIOMEDICAL Q3 BIOPHYSICS

最新[2023]版：

Q3 ENGINEERING, BIOMEDICAL Q3 BIOPHYSICS

影响因子： 2.4 最新[2023版] 2.5 最新五年平均 2.463 出版当年[2010版] 3.252 出版当年五年平均 2.657 出版前一年[2009版] 2.434 出版后一年[2011版]

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第一作者机构： [1]Department of Mechanical Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong

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