Objective: The purpose of this study was to investigate the auditory performance of infants with isolated Large Vestibular Aqueduct Syndrome (LVAS) after cochlear implantation, compare their performance with those of infants with a normal inner ear, and establish a database of auditory developrnent. Method: 435 infants with congenital severe to profound hearing loss participated in this study. 62 infants in group A were diagnosed with isolated LVAS. 373 infants in group B had a normal inner ear. Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS) was used to evaluate the development of auditory skills. Results: The mean scores for auditory ability showed no significant difference between groups A and B. The mean scores for the three different auditory skills increased significantly over time. The differences were statistically significant in mean scores among the three different auditory skills for group B. Conclusion: Auditory skills of infants with isolated LVAS developed rapidly after cochlear implantation, in a similar manner to those of infants with a normal inner ear. Cochlear implantation is an effective interventional approach and an established therapeutic option for infants with isolated LVAS. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
基金：
the promotion grant (2009-3-29) for high-level scientific and technological elites in medical science from the Beijing Health Bureau
第一作者机构：[1]Beijing Inst Otolaryngol, Minist Educ, Key Lab Otolaryngol Head & Neck Surg, Beijing 100005, Peoples R China
通讯作者：
通讯机构：[1]Beijing Inst Otolaryngol, Minist Educ, Key Lab Otolaryngol Head & Neck Surg, Beijing 100005, Peoples R China[2]Capital Med Univ, Beijing Tongren Hosp, Beijing 100730, Peoples R China[*1]Beijing Inst Otolaryngol, Minist Educ, Key Lab Otolaryngol Head & Neck Surg, 17 HouGouHuTong, Beijing 100005, Peoples R China
推荐引用方式(GB/T 7714)：
Chen Xueqing,Liu Bo,Liu Sha,et al.The development of auditory skills in infants with isolated Large Vestibular Aqueduct Syndrome after cochlear implantation[J].INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY.2011,75(7):943-947.doi:10.1016/j.ijporl.2011.04.015.
APA：
Chen, Xueqing,Liu, Bo,Liu, Sha,Mo, Lingyan,Liu, Haihong...&Zhang, Luo.(2011).The development of auditory skills in infants with isolated Large Vestibular Aqueduct Syndrome after cochlear implantation.INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY,75,(7)
MLA：
Chen, Xueqing,et al."The development of auditory skills in infants with isolated Large Vestibular Aqueduct Syndrome after cochlear implantation".INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY 75..7(2011):943-947
