机构：[1]Department of Ophthalmology, Peking University People’s Hospital, Eye diseases and optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.[2]Peking University First Hospital, Beijing 100034, China.[3]Department of Ophthalmology, Peking University People’s Hospital, No. 11 S Ave of XiZhiMen, XiCheng District, Beijing 100044, People’s Republic of China.
To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence tomography angiography (OCTA).There were 60 eyes of 31 volunteers enrolled in this cross-sectional observational study. All subjects underwent OCTA, AL and refraction test. The enrolled eyes were divided into the long AL group (26 mm ≤ AL < 28 mm) and normal AL group (22 mm ≤ AL < 26 mm). The vessel length density (VLD), perfusion density (PD), and fovea avascular zone (FAZ) of the superficial retinal vessel were evaluated. Repeatability was assessed by intraclass correlation coefficients (ICCs) and Bland-Altman analysis. Pearson's r correlation was used to analyze the relation of AL and the absolute difference between two measurements.The 3 × 3 mm scan pattern showed good repeatability with all ICCs over 0.7. For all parameters of all scan patterns, the ICCs of the normal AL group were distinctly higher than those of the long AL group; this finding was also confirmed by Bland-Altman analysis. The correlation analysis of AL and repeatability of OCTA parameters showed significant negative correlations between the ALs and repeatability of VLD in 6 × 6 mm inner ring (r2 = 0.13, p = 0.01), VLD in 6 × 6 mm outer ring (r2 = 0.09, p = 0.02) and PD in 6 × 6 mm outer ring (r2 = 0.08, p = 0.03).The AL and the scanned area will both affect the repeatability of superficial retinal vessel density measurements in OCTA.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|4 区医学
小类|4 区眼科学
最新[2023]版：
大类|4 区医学
小类|3 区眼科学
第一作者：
第一作者机构：[1]Department of Ophthalmology, Peking University People’s Hospital, Eye diseases and optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.
通讯作者：
通讯机构：[1]Department of Ophthalmology, Peking University People’s Hospital, Eye diseases and optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.[3]Department of Ophthalmology, Peking University People’s Hospital, No. 11 S Ave of XiZhiMen, XiCheng District, Beijing 100044, People’s Republic of China.
推荐引用方式(GB/T 7714)：
Li Mengyang,Jin Enzhong,Dong Chongya,et al.The repeatability of superficial retinal vessel density measurements in eyes with long axial length using optical coherence tomography angiography.[J].BMC ophthalmology.2018,18(1):326.doi:10.1186/s12886-018-0992-y.
APA：
Li Mengyang,Jin Enzhong,Dong Chongya,Zhang Chuan,Zhao Mingwei&Qu Jinfeng.(2018).The repeatability of superficial retinal vessel density measurements in eyes with long axial length using optical coherence tomography angiography..BMC ophthalmology,18,(1)
MLA：
Li Mengyang,et al."The repeatability of superficial retinal vessel density measurements in eyes with long axial length using optical coherence tomography angiography.".BMC ophthalmology 18..1(2018):326
