Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography
Objective The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography (OCTA) based on optical microangiography (OMAG) measurements of macular vessels in normal eyes. Methods In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA (Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three times. The following parameters were used to quantitatively describe the OCTA images of the superficial vascular network: vessel area density (VAD), vessel skeleton density (VSD), vessel diameter index (VDI), vessel perimeter index (VPI), vessel complexity index (VCI), flux, and foveal avascular zone (FAZ). Coefficient of variation (CV) and intraclass correlation coefficient (ICC) were calculated for evaluating intravisit and intervisit repeatability, as well as interobserver reproducibility. Results The measurements showed high repeatability [CVs <= 4.2% (intravisit) and <= 4.6% (intervisit)] and interobserver reproducibility (ICCs >= 0.923) for all parameters. Conclusion This study demonstrated good repeatability and reproducibility of OCTA based on OMAG for the measurement of superficial vessel parameters in normal eyes.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81570891, 81272981]; Beijing Natural Science FoundationBeijing Natural Science Foundation [7151003]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|3 区环境科学与生态学
小类|3 区环境科学3 区公共卫生、环境卫生与职业卫生
最新[2025]版：
大类|4 区医学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
JCR分区：
出版当年[2016]版：
Q2ENVIRONMENTAL SCIENCESQ2PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
最新[2023]版：
Q2ENVIRONMENTAL SCIENCESQ2PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者机构：[1]Capital Med Univ,Beijing Tongren Hosp,Beijing Tongren Eye Ctr,Dept Ophthalmol,Beijing 100730,Peoples R China[2]Beijing Key Lab Ophthalmol & Visual Sci, Beijing 100730, Peoples R China
通讯作者：
通讯机构：[1]Capital Med Univ,Beijing Tongren Hosp,Beijing Tongren Eye Ctr,Dept Ophthalmol,Beijing 100730,Peoples R China[2]Beijing Key Lab Ophthalmol & Visual Sci, Beijing 100730, Peoples R China
推荐引用方式(GB/T 7714)：
Zhao Qi,Yang Wen Li,Wang Xiao Na,et al.Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography[J].BIOMEDICAL AND ENVIRONMENTAL SCIENCES.2018,31(6):407-412.doi:10.3967/bes2018.054.
APA：
Zhao Qi,Yang Wen Li,Wang Xiao Na,Wang, Ruikang K.,You Qi Sheng...&Wei Wen Bin.(2018).Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography.BIOMEDICAL AND ENVIRONMENTAL SCIENCES,31,(6)
MLA：
Zhao Qi,et al."Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography".BIOMEDICAL AND ENVIRONMENTAL SCIENCES 31..6(2018):407-412
