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Status of Immunotherapy Acceptance in Chinese Patients With Multiple Sclerosis: Analysis of Multiple Sclerosis Patient Survival Report 2018(Open Access)

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机构: [1]Department of Neurology, Xiangya Hospital, Central South University, Changsha, China, [2]Department of Neurology, PekingUnion Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, [3]Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China, [4]Department ofNeurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, [5]Department of Neurology, The SecondAffiliated Hospital, Harbin Medical University, Harbin, China, [6]Department of Neurology, West China Hospital, SichuanUniversity, Chengdu, China, [7]Department of Neurology, The First Affiliated Hospital of Shanxi Medical University, Taiyuan,China, [8]Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, [9]Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China, [10]Departmentof Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, [11]Department of Neurology, Beijing TongrenHospital, Capital Medical University, Beijing, China, [12]Department of Neurology, The First Affiliated Hospital of WenzhouMedical University, Wenzhou, China, [13]Department of Neurology, Peking University First Hospital, Beijing, China, [14]Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China, [15]Department of Neurology, TongjiHospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, [16]Department ofNeurology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China, [17]Department of Neurology, XuanwuHospital, Capital Medical University, Beijing, China, [18]Department of Neurology, The First Affiliated Hospital of Fujian MedicalUniversity, Fuzhou, China, [19]Department of Neurology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou,China, [20]Department of Neurology, General Hospital of the People’s Liberation Army, Beijing, China, [21]Department ofNeurology, The Second Hospital of Lanzhou University, Lanzhou, China, [22]Department of Neurology, The First AffiliatedHospital, Guangxi Medical University, Nanning, China, [23]Department of Neurology, Nanfang Hospital, Southern MedicalUniversity, Guangzhou, China, [24]Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou, China, [25]Department of Neurology, The First Affiliated Hospital, Dalian Medical University, Dalian, China, [26]Department of Neurology, Affiliated Zhongshan Hospital, Xiamen University, Xiamen, China
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关键词: disease-modifying therapies drug selection immunosuppressive drug multicenter study multiple sclerosis

摘要:
Objective: The prevalence of multiple sclerosis (MS) in China is low, although it has been increasing recently. Owing to the paucity of data on immunotherapy acceptance in the Chinese population, we conducted this study to analyze factors affecting the acceptance of immunotherapy and selection of disease-modifying therapies (DMTs) based on personal and clinical data of patients with MS. Methods: In this study, data were obtained from the Multiple Sclerosis Patient Survival Report 2018, which was the first national survey of patients with MS in China. There were 1,212 patients with MS from 31 provinces who were treated at 49 Chinese hospitals over a 4-month period from May 2018 to August 2018, and the patients were asked to complete online questionnaires to assess their understanding of the disease. Results: In general, highly educated patients with frequent relapses were more willing to receive treatment regardless of DMTs or other immunotherapy, and patients with more understanding of the disease opted to be treated. Younger patient population, patients with severe disease course, and those with more symptoms were likely to choose the treatment. Moreover, a higher proportion of women chose to be treated with DMTs than with other immunotherapies. Conclusions: Education status and patient awareness of the disease impact the treatment acceptance in Chinese patients with MS. Therefore, we call for improving the awareness of MS disease and social security to help patients to improve their quality of life. © Copyright © 2021 Zhou, Zeng, Yang, Xu, Tan, Liu, Wang, Zhou, Zhang, Feng, Jin, Zhang, Wang, Zhang, Gao, Yang, Bu, Li, Zhang, Dong, Lin, Liu, Wu, Wang, Tang, Wang, Long, Wang and Zheng.

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出版当年[2020]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 神经科学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 神经科学
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出版当年[2019]版:
Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES
最新[2023]版:
Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

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第一作者机构: [1]Department of Neurology, Xiangya Hospital, Central South University, Changsha, China,
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