Study Objectives: The aim of the study was to inspect the acoustic properties and sleep characteristics of a preapneic snoring sound. The feasibility of forecasting upcoming respiratory events by snoring sound was also investigated. Methods: Participants with habitual snoring or a heavy breathing sound during sleep were recruited consecutively. Polysomnography was conducted, and snoring-related breathing sound was recorded simultaneously. Acoustic features and sleep features were extracted from 30-second samples, and a machine learning algorithm was used to establish 2 prediction models. Results: A total of 74 eligible participants were included. Model 1, tested by 5-fold cross-validation, achieved an accuracy of 0.92 and an area under the curve of 0.94 for respiratory event prediction. Model 2, with acoustic features and sleep information tested by Leave-One-Out cross-validation, had an accuracy of 0.78 and an area under the curve of 0.80. Sleep position was found to be the most important among all sleep features contributing to the performance of the 2 models. Conclusions: Preapneic sound presented unique acoustic characteristics, and snoring-related breathing sound could be deployed as a real-time apneic event predictor. The models, combined with sleep information, serve as a promising tool for an early warning system to forecast apneic events.
基金:
National Key Research and Development Program of China [2018YFC0116800]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81970866]; Beijing Municipal Administration of Hospitals' Youth Programme [QMS20190202]; Beijing Municipal Natural Science FoundationBeijing Natural Science Foundation [L192026]
第一作者机构:[1]Capital Med Univ, Beijing Tongren Hosp, 1 Dongjiaominxiang, Beijing, Peoples R China[2]Capital Med Univ, Obstruct Sleep Apnea Hypopnea Syndrome Clin Diag, Beijing, Peoples R China[3]Capital Med Univ, Key Lab Otolaryngol Head & Neck Surg, Minist Educ, Beijing, Peoples R China
共同第一作者:
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tongren Hosp, 1 Dongjiaominxiang, Beijing, Peoples R China[2]Capital Med Univ, Obstruct Sleep Apnea Hypopnea Syndrome Clin Diag, Beijing, Peoples R China[3]Capital Med Univ, Key Lab Otolaryngol Head & Neck Surg, Minist Educ, Beijing, Peoples R China[4]Tsinghua Univ, Dept Elect Engn, Beijing, Peoples R China[5]Tsinghua Univ, Ctr Big Data & Clin Res, Inst Precis Med, Beijing, Peoples R China[*1]Beijing Tongren Hospital, Capital Medical University, 1 Dongjiaominxiang, Dongcheng District, Beijing, People’s Republic of China[*2]Room 8301, Luomu Building, Tsinghua University, Haidian District, Beijing, People’s Republic of China
推荐引用方式(GB/T 7714):
Wang Bochun,Yi Xuanyu,Gao Jiandong,et al.Real-time prediction of upcoming respiratory events via machine learning using snoring sound signal[J].JOURNAL OF CLINICAL SLEEP MEDICINE.2021,17(9):1777-1784.doi:10.5664/jcsm.9292.
APA:
Wang, Bochun,Yi, Xuanyu,Gao, Jiandong,Li, Yanru,Xu, Wen...&Han, Demin.(2021).Real-time prediction of upcoming respiratory events via machine learning using snoring sound signal.JOURNAL OF CLINICAL SLEEP MEDICINE,17,(9)
MLA:
Wang, Bochun,et al."Real-time prediction of upcoming respiratory events via machine learning using snoring sound signal".JOURNAL OF CLINICAL SLEEP MEDICINE 17..9(2021):1777-1784