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Retrocorneal membrane interception enhanced penetrating canaloplasty for patients with open angle glaucoma secondary to ICE syndrome

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机构: [1]The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China. [2]Glaucoma Research Institute, Wenzhou Medical University, Wenzhou, China. [3]National Clinical Research Center for Ocular Diseases, Glaucoma Research Institute of Wenzhou Medical University, The Eye Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. [4]Department of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. [5]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China. [6]Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Institute of Ophthalmology, Capital Medical University, No. 1 Dongjiaominxiang Street, Beijing, 100730, Dongcheng District, China. [7]Beijing Institute of Ophthalmology, Beijing, China. [8]The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China. [9]Glaucoma Research Institute, Wenzhou Medical University, Wenzhou, China. [10]National Clinical Research Center for Ocular Diseases, Glaucoma Research Institute of Wenzhou Medical University, The Eye Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
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关键词: Bleb-independent filtering surgery Intraocular pressure Penetrating canaloplasty Retrocorneal membrane interception Iridocorneal endothelial syndrome Glaucoma

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To assess the efficacy and safety of retrocorneal membrane interception (RMI)-enhanced penetrating canaloplasty in glaucoma secondary to iridocorneal endothelial syndrome (GS-ICE) with open angle or small peripheral anterior synechiae (PAS).A series of 13 patients (13 eyes) with GS-ICE and uncontrolled intraocular pressure (IOP) underwent RMI-enhanced penetrating canaloplasty from March 2019 to October 2020. The patients were followed up at one week, 1 month, 3 months, 6 months, and 12 months, postoperatively. The main outcome measure was surgical success, which was defined as an IOP ≤ 18 mmHg or ≤ 21 mmHg, with glaucoma medications (qualified success), or without glaucoma medications (complete success). Secondary outcome measures were IOP, medication usage, and surgical complications.Among the 13 GS-ICE eyes, 12 (92%) achieved qualified success and 10 (77%) achieved complete success at 12 months postoperatively. The mean IOP decreased from 36.41 ± 8.92 mmHg on 3.0 (IQR 0.5) medications before surgery to 17.09 ± 7.71 mmHg (p = 0.0004) on 0.0 (IQR 0.5) medications (p = 0.0004) at 12 months after surgery. Transient hypotony (38%) and hyphema (38%) were the most common complications.RMI-enhanced penetrating canaloplasty appears effective and safe in treating GS-ICE with open angle or small PAS up to one year of follow up.© 2024. The Author(s), under exclusive licence to Springer Nature B.V.

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出版当年[2023]版:
大类 | 4 区 医学
小类 | 4 区 眼科学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 眼科学
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Q4 OPHTHALMOLOGY
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Q3 OPHTHALMOLOGY

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第一作者机构: [1]The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China. [2]Glaucoma Research Institute, Wenzhou Medical University, Wenzhou, China. [3]National Clinical Research Center for Ocular Diseases, Glaucoma Research Institute of Wenzhou Medical University, The Eye Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
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通讯机构: [6]Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Institute of Ophthalmology, Capital Medical University, No. 1 Dongjiaominxiang Street, Beijing, 100730, Dongcheng District, China. [7]Beijing Institute of Ophthalmology, Beijing, China. [8]The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China. [9]Glaucoma Research Institute, Wenzhou Medical University, Wenzhou, China. [10]National Clinical Research Center for Ocular Diseases, Glaucoma Research Institute of Wenzhou Medical University, The Eye Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
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