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Controversies, Consensuses, and Guidelines on Preventing, Diagnosing and Managing Acute-onset Bacterial Endophthalmitis after Cataract Surgery by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII)

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Pubmed体系：
作者：
Namrata Sharma[1] * ; Aafreen Bari[1] * ; Srinivas K. Rao[2] ; Rupesh Agrawal[3,4,5,6,7] ; Penelope J. Allen[8,9,10] ; John C. Buchan[11,12,13] ; Andrew Chang[14] ; David F. Chang[15] ; Soon-Phaik Chee[16,17,18] ; Weirong Chen[19] ; Kuan-Jen Chen[20,21] ; Vanissa W. S. Chow[22,23] ; Taraprasad Das[24,25] ; Vivek P. Dave[24] ; Harry W. Flynn Jr[26] ; Tina Felfeli[27,28] ; Adrian T. Fung[29,30,31] ; Andrzej Grzybowski[32,33] ; Mary Ho[22,34] ; Wai Ching Lam[35] ; Liying Low[36,37] ; Mats Lundström[38] ; William F. Mieler[39] ; Nishant V. Radke[40] ; Paisan Ruamviboonsuk[41] ; Landon J. Rohowetz[26] ; Savitri Sharma[42] ; Tarun Sharma[43] ; Takashi Suzuki[44,45] ; Chi Wai Tsang[22,23] ; Ke Yao[46] ; Alvin L. Young[22,34] ; Mingzhi Zhang[47] ; Ke Zheng[48] ; Dennis S. C. Lam[40,49,50] ;
机构： [1]Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India [2]Darshan Eye Care & Surgical Centre, Chennai, India [3]National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore [4]Programme for Ocular Inflammation & Infection Translational Research, National Healthcare Group Eye Institute, Singapore [5]Duke-NUS Medical School, Singapore [6]Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore [7]Singapore Eye Research Institute, Singapore [8]Centre for Eye Research Australia, Royal Victorian Eye & Ear Hospital, East Melbourne, VIC, Australia [9]Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, VIC, Australia [10]Vitreoretinal Unit, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC, Australia. [11]Department of Ophthalmology, Leeds Teaching Hospitals NHS Trust, Leeds, UK [12]The Royal College of Ophthalmologists' National Ophthalmology Database Audit, London, UK [13]International Centre for Eye Health, LSHTM, London, UK [14]Sydney Retina Clinic, Sydney Eye Hospital, University of Sydney, Sydney, NSW, Australia [15]Altos Eye Physicians (D.F.C.), Los Altos, California, USA [16]Department of Ophthalmology, National University Hospital, Singapore [17]Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore [18]Singapore National Eye Centre, Singapore [19]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China [20]Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan [21]College of Medicine, Chang Gung University, Taoyuan, Taiwan [22]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China [23]Hong Kong Eye Hospital, Kowloon, Hong Kong, China [24]Department of Ophthalmology, LV Prasad Eye Institute, Kalam Anji Reddy Campus, Anant Bajaj Retina Institute, Srimati Kanuri Santhmma Centre for Vitreoretinal Diseases, Hyderabad, Telangana, India [25]Shantilal Shanghvi Eye Institute, Mumbai, India [26]Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, US [27]Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada [28]The Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada [29]Save Sight Institute, Specialty of Clinical Ophthalmology and Eye Health, The University of Sydney, Sydney, New South Wales, Australia [30]Department of Ophthalmology, Westmead Hospital, Sydney, New South Wales, Australia [31]Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia [32]Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan, Poland [33]Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland [34]Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China [35]Department of Ophthalmology, Vancouver Acute, University of British Columbia, Canada [36]Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom [37]Birmingham and Midland Eye Centre, Sandwell and West Birmingham NHS Trust, Birmingham, United Kingdom [38]Department of Clinical Sciences, Ophthalmology, Faculty of Medicine, Lund University, Lund, Sweden [39]Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago [40]The Primasia International Eye Research Institute (PIERI) of The Chinese University of Hong Kong (Shenzhen), Shenzhen, China [41]Retina Division, Department of Ophthalmology, Faculty of Medicine, Rajvithi hospital, Rangsit University, Bangkok, Thailand [42]Jhaveri Microbiology Center, L V Prasad Eye Institute, Hyderabad, India [43]Department of Ophthalmology, Columbia University, New York, NY, USA [44]Department of Ophthalmology, Toho University Faculty of Medicine, Tokyo, Japan [45]Ishizuchi Eye Clinic, Niihama, Ehime, Japan [46]Zhejiang University, Eye Center of Second Affiliated Hospital, School of Medicine, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, China [47]Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China [48]The C-MER (Beijing) Dennis Lam Eye Hospital, Shenzhen, Guangdong, China [49]The C-MER Dennis Lam and Partners Eye Center, C-MER International Eye Care Group, Hong Kong, China [50]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China
出处：
DOI： 10.1016/j.ajo.2025.08.031
ISSN：

关键词： post-cataract surgery endophthalmitis prophylaxis diagnosis management AAPPO APVRS APSOII

摘要：
Post-cataract surgery endophthalmitis is a serious but largely preventable clinical entity. The implementation of uniform pre-operative, intra-operative, and post-operative protocols is essential to reduce its incidence. In light of emerging evidence and considerable variability in clinical practices, a panel of international experts from the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII) convened to develop evidence-based guidelines addressing all phases of cataract surgery. This consensus manuscript is the product of a systematic review of the current literature, informed by the collective experience and expertise of the panel members. The panel engaged in structured discussions, critical evaluation of clinical data, and formal voting to establish agreement across three key domains: (1) pre-operative and intra-operative prophylactic strategies, (2) diagnostic approaches for early post-operative acute bacterial endophthalmitis, and (3) standardized management protocols. Voting on each proposed statement was conducted using a five-point Likert scale (strongly agree, agree, neutral, disagree, strongly disagree). Consensus was defined as ≥75% of experts voting either "strongly agree" or "agree." A total of 45 consensus statements were evaluated, of which 21 (46.6%) achieved the predefined level of consensus. This document aims to establish standardized guidelines to improve cataract surgery outcomes by minimizing the risk of post-operative endophthalmitis. For areas where consensus was not achieved, the panel recommends further investigation and continued research to guide future updates to clinical practice.Copyright © 2025. Published by Elsevier Inc.

基金：
Ms. May Lam Research and Education Fund of The Primasia International Eye Research Institute (PIERI) of The Chinese University of Hong Kong (Shenzhen); Shun Hing Education and Charity Fund; Bright Future Charitable Foundation Postgraduate Education Fund; Daniel & Co Scholarship
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
大类 | 1 区 医学
小类 | 1 区 眼科学
最新[2025]版：
大类 | 1 区 医学
小类 | 1 区 眼科学
第一作者：
第一作者机构： [1]Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
共同第一作者：
通讯作者：
通讯机构： [40]The Primasia International Eye Research Institute (PIERI) of The Chinese University of Hong Kong (Shenzhen), Shenzhen, China [49]The C-MER Dennis Lam and Partners Eye Center, C-MER International Eye Care Group, Hong Kong, China [50]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China
推荐引用方式(GB/T 7714)：
Namrata Sharma,Aafreen Bari,Srinivas K. Rao,et al.Controversies, Consensuses, and Guidelines on Preventing, Diagnosing and Managing Acute-onset Bacterial Endophthalmitis after Cataract Surgery by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII)[J].American Journal Of Ophthalmology.2025,doi:10.1016/j.ajo.2025.08.031.
APA：
Namrata Sharma,Aafreen Bari,Srinivas K. Rao,Rupesh Agrawal,Penelope J. Allen...&Dennis S. C. Lam.(2025).Controversies, Consensuses, and Guidelines on Preventing, Diagnosing and Managing Acute-onset Bacterial Endophthalmitis after Cataract Surgery by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII).American Journal Of Ophthalmology,,
MLA：
Namrata Sharma,et al."Controversies, Consensuses, and Guidelines on Preventing, Diagnosing and Managing Acute-onset Bacterial Endophthalmitis after Cataract Surgery by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII)".American Journal Of Ophthalmology .(2025)

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