Aim: This study aimed to report the preliminary surgical outcomes of a new minimally invasive glaucoma surgery (MIGS), namely trabeculotome tunneling trabeculoplasty (3T) in primary open-angle glaucoma (POAG). Methods: This retrospective observational study with prospective follow-up included POAG patients who underwent 3T surgery at Chengdu First People's Hospital between December 2022 and June 2024. Postoperative follow-up was conducted at 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months. Evaluations included intraocular pressure (IOP), number of medications, surgical success rate, and postoperative complications. Results: Baseline mean IOP was 23.06 +/- 0.72 mmHg with a median of 3 (interquartile range, IQR: 2-3) medications. Postoperative IOP significantly decreased at all follow-up points except at 1 week (p < 0.05). At 12 months, the mean IOP was 16.22 +/- 0.76 mmHg with a median of 0 (IQR: 0-1) medications. Complete surgical success rates were 80.0% at 6 months and 79.8% at 12 months. Early postoperative complications included IOP spikes in 34.9% and clinically significant hyphema in 6.3% (all grade 1). Cyclodialysis was rare (1.1%), and no severe adverse events were reported. Conclusion: 3T appears to be a safe and effective surgical option for POAG, providing sustained IOP reduction and medication burden relief with a low incidence of postoperative complications. Larger, controlled studies with longer follow-up are warranted to further validate these findings.
基金:
Research Project of Sichuan Provincial Administration of Traditional Chinese Medicine; [2024MS471]
第一作者机构:[1]Chengdu Integrated TCM & Western Med Hosp, Dept Ophthalmol, Chengdu, Peoples R China
共同第一作者:
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推荐引用方式(GB/T 7714):
Wang Suzhen,Qiu Qin,He Yu,et al.Safety and effectiveness of a new minimally invasive glaucoma surgery namely trabeculotome tunneling trabeculoplasty in primary open-angle glaucoma[J].FRONTIERS IN MEDICINE.2025,12:doi:10.3389/fmed.2025.1641952.
APA:
Wang, Suzhen,Qiu, Qin,He, Yu,Fan, Hanying,Jing, Lin...&Wang, Ningli.(2025).Safety and effectiveness of a new minimally invasive glaucoma surgery namely trabeculotome tunneling trabeculoplasty in primary open-angle glaucoma.FRONTIERS IN MEDICINE,12,
MLA:
Wang, Suzhen,et al."Safety and effectiveness of a new minimally invasive glaucoma surgery namely trabeculotome tunneling trabeculoplasty in primary open-angle glaucoma".FRONTIERS IN MEDICINE 12.(2025)