Introduction The pregnancy and lactation-associated osteoporosis (PLO) is a rare disease whose precise pathophysiological mechanisms remain mostly unknown. Case report We reported here a case of PLO that occurred in the early postpartum period and led to multiple compression fractures. Combination therapy with alendronate, calcium carbonate, and vitamin D was used to treat the patient and a marked but gradual increase in the density of bone mineral was observed. Moreover, no further fractures have occurred. Conclusion PLO is a very rare type of osteoporosis associated with severe chronic back pain. Increased bone resorption significantly increases the risk of bone fractures in women with PLO. Early diagnosis, stopping breastfeeding, treatment of calcium and vitamin D, bisphosphonates, or other antiosteoporosis medicine and regular follow-ups of these cases are particularly important in the prevention of fractures and to increase the quality of life of patients.
第一作者机构：[1]Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong’an Road, Xicheng District, Beijing, China
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推荐引用方式(GB/T 7714)：
Jia Pu,Wang RuiDeng,Yuan Jing,et al.A case of pregnancy and lactation-associated osteoporosis and a review of the literature[J].ARCHIVES OF OSTEOPOROSIS.2020,15(1):doi:10.1007/s11657-020-00768-7.
APA：
Jia, Pu,Wang, RuiDeng,Yuan, Jing,Chen, Hao,Bao, Li...&Tang, Hai.(2020).A case of pregnancy and lactation-associated osteoporosis and a review of the literature.ARCHIVES OF OSTEOPOROSIS,15,(1)
MLA：
Jia, Pu,et al."A case of pregnancy and lactation-associated osteoporosis and a review of the literature".ARCHIVES OF OSTEOPOROSIS 15..1(2020)
