机构：[1]Department of Neurology, Shanghai TongRen Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China[2]Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
Sleep disorders are one of the most common non-motor symptoms in Parkinson's disease (PD). It can cause a notable decrease in quality of life and functioning in PD patients, as well as place a huge burden on both patients and caregivers. The most cited sleep disorders in PD included insomnia, restless legs syndrome (RLS), rapid eye movement (REM), sleep behavior disorders (RBD), excessive daytime sleepiness (EDS) and sleep disordered breathing (SDB), which can ap-pear alone or several at the same time. In this review, we listed the recommended pharmacological treatments for common sleep disorders in PD, and discussed the recommended dosages, benefits and side effects of relative drugs. We also discussed non-pharmacological treatments to improve sleep quality, including sleep hygiene education, exercise, deep brain stimulation, cognitive behav-ior therapy and complementary therapies. We tried to find proper interventions for different types of sleep disorders in PD, while minimizing relative side effects.
基金：
National Natural Science Foundation of China (NSFC) [81671251]
第一作者机构：[1]Department of Neurology, Shanghai TongRen Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China
通讯作者：
通讯机构：[1]Department of Neurology, Shanghai TongRen Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China[*1]Department of Neurology, Shanghai TongRen Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China
推荐引用方式(GB/T 7714)：
Taximaimaiti Reyisha,Luo Xingguang,Wang Xiao-Ping.Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease[J].CURRENT NEUROPHARMACOLOGY.2021,19(12):2233-2249.doi:10.2174/1570159X19666210517115706.
APA：
Taximaimaiti, Reyisha,Luo, Xingguang&Wang, Xiao-Ping.(2021).Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease.CURRENT NEUROPHARMACOLOGY,19,(12)
MLA：
Taximaimaiti, Reyisha,et al."Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease".CURRENT NEUROPHARMACOLOGY 19..12(2021):2233-2249
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