机构：[1]School of Biomedical Engineering, Capital Medical University, Beijing, China,[2]Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing, China,[3]Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China,[4]Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China,首都医科大学附属北京同仁医院研究所眼科研究所[5]Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beijing Tongren Hospital, Beihang University and Capital Medical University, Beijing, China,首都医科大学附属北京同仁医院首都医科大学附属同仁医院[6]Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Background: To compare the corneal biomechanics of thin normal cornea (TNC) with thinnest corneal thickness (TCT) (<= 500 mu m), forme-fruste keratoconus (FFKC) and cornea after small incision lenticule extraction (Post-SMILE) had their central corneal thickness (CCT) matched by Corneal Visualization Scheimpflug Technology (Corvis ST).Methods: CCT were matched in 23 eyes with FFKC, 23 eyes by SMILE in 3 months post-operatively, and 23 TNC eyes. The differences in corneal biomechanics by Corvis ST among the three groups were compared.Results: There was no significant difference in CCT among the three groups, and the biomechanically corrected intraocular pressure (bIOP) did not differ significantly among the three groups (all p > 0.05). There were significant differences in most DCR parameters between pre- and post-operatively (all p < 0.05). Compared with TNC, the values of corneal deflection amplitude during the first applanation (A1DA), length at the first applanation (A1L), corneal deflection amplitude during the second applanation (A2DA), and maximum deformation amplitude (DA) decreased in 3 months after SMILE (all p < 0.05), these values increased in the FFKC (all p < 0.05).Conclusion: The majority of the DCR parameters were different among the three groups. The parameters A1DA, A1L, A2DA, and DA may be different between TNC and Post-SMILE, TNC and FFKC, and Post-SMILE and FFKC.
基金：
National Natural
Science Foundation of China (Nos 32171304, 31370952,
31470914, 31600758, 82171101); Beijing Nova Program
(Z181100006218099); the Open Research Fund from Beijing
Advanced Innovation Center for Big Data-Based Precision
Medicine, Beijing Tongren Hospital, Beihang University and
Capital Medical University (BHTR-KFJJ-202001).
第一作者机构：[1]School of Biomedical Engineering, Capital Medical University, Beijing, China,[2]Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing, China,[3]Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China,
共同第一作者：
通讯作者：
通讯机构：[1]School of Biomedical Engineering, Capital Medical University, Beijing, China,[2]Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing, China,[3]Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China,
推荐引用方式(GB/T 7714)：
Zhang Di,Tian Lei,Zhang Haixia,et al.Differences of Corneal Biomechanics Among Thin Normal Cornea, Forme-Fruste Keratoconus, and Cornea After SMILE[J].FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY.2022,10:doi:10.3389/fbioe.2022.861924.
APA：
Zhang, Di,Tian, Lei,Zhang, Haixia,Zheng, Yan,Fu, Caiyun...&Li, Lin.(2022).Differences of Corneal Biomechanics Among Thin Normal Cornea, Forme-Fruste Keratoconus, and Cornea After SMILE.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,10,
MLA：
Zhang, Di,et al."Differences of Corneal Biomechanics Among Thin Normal Cornea, Forme-Fruste Keratoconus, and Cornea After SMILE".FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 10.(2022)
