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Intra-aortic balloon pump reduces 30-day mortality in early stage cardiogenic shock complicating acute myocardial infarction according to SCAI classification

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机构: [1]Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China [2]Cardiovascular Research Institute of Wuhan University, Wuhan, China [3]Hubei Key Laboratory of Cardiology, Wuhan, China [4]Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China [5]Taikang Tongji (Wuhan) Hospital, Wuhan, China [6]Three Gorges University & Yichang Central People's Hospital, Yichang, China [7]Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China [8]The No1. People's Hospital of Xiangyang, Xiangyang, China [9]The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, China [10]Wuhan Third Hospital & Tongren Hospital of Wuhan University, Wuhan, China
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关键词: intra-aortic balloon pump cardiogenic shock acute myocardial infarction mortality SCAI shock stage

摘要:
Cardiogenic shock complicating acute myocardial infarction (AMICS) remains a high 30-day mortality. Mechanical circulatory support devices are increasingly used in AMICS, but their effects on mortality vary partly due to shock severity.This study aimed to evaluate the association between intra-aortic balloon pump (IABP) and 30-day mortality in patients with early stage AMICS.We retrospectively analyzed patients with ST-segment elevation myocardial infarction (STEMI) based on a multicenter clinical trial (NCT04996901). Patients were stratified by IABP use and shock severity was classified according to the Society for Cardiovascular Angiography and Interventions (SCAI) SHOCK stages. The primary outcome was 30-day all-cause mortality. The association between IABP and 30-day mortality was evaluated across shock stages using propensity score matching, weighting, and logistic regression.5343 patients were included and 299 received IABP. SCAI SHOCK stage was associated with 30-day mortality (OR 20.19, 95%CI 13.60-29.97, P < 0.001). In the 580 matched patients, a significant interaction between IABP and 30-day mortality at different shock stages was observed (P = 0.005). IABP was associated with lower 30-day mortality among patients with shock stage A/B (5.8% vs. 1.2%, OR 0.19, 95%CI 0.03-0.73, P = 0.034) but not stage C/D/E (29.3% vs. 38.1%, OR 1.49, 95%CI 0.84-2.65, P = 0.172). These results were confirmed by sensitivity analyses of the weighted cohort.IABP reduced 30-day mortality in patients with early stage AMICS. The SCAI SHOCK stage provides risk stratification for patients with STEMI and helps identify those who may respond well to IABP.Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Shock Society.

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出版当年[2022]版:
大类 | 2 区 医学
小类 | 2 区 外科 2 区 血液学 3 区 外周血管病 3 区 危重病医学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 血液学 3 区 外周血管病 3 区 外科 4 区 危重病医学
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出版当年[2021]版:
Q1 SURGERY Q2 PERIPHERAL VASCULAR DISEASE Q3 CRITICAL CARE MEDICINE Q3 HEMATOLOGY
最新[2023]版:
Q1 SURGERY Q2 CRITICAL CARE MEDICINE Q2 HEMATOLOGY Q2 PERIPHERAL VASCULAR DISEASE

影响因子: 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

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第一作者机构: [1]Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China [2]Cardiovascular Research Institute of Wuhan University, Wuhan, China [3]Hubei Key Laboratory of Cardiology, Wuhan, China
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通讯机构: [1]Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China [2]Cardiovascular Research Institute of Wuhan University, Wuhan, China [3]Hubei Key Laboratory of Cardiology, Wuhan, China [*1]Department of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan 430060, PR China.
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