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Understanding the complex genetics and molecular mechanisms underlying glaucoma

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WOS体系：
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收录情况： ◇ SCIE

作者：
Wang Weiwei[1] * ; Wang Huaizhou[2] ;
机构： [1]Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated People's Hospital, Northwest University, Xi'an, 710004, Shaanxi Province, China. [2]Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
出处：
DOI： 10.1016/j.mam.2023.101220
ISSN：

关键词： Glaucoma Optic nerve Intraocular pressure Genetics Mitochondria

摘要：
Glaucoma is the leading cause of irreversible blindness worldwide. Currently the only effective treatment for glaucoma is to reduce the intraocular pressure, which can halt the progression of the disease. Highlighting the importance of identifying individuals at risk of developing glaucoma and those with early-stage glaucoma will help patients receive treatment before sight loss. However, some cases of glaucoma do not have raised intraocular pressure. In fact, glaucoma is caused by a variety of different mechanisms and has a wide range of different subtypes. Understanding other risk factors, the underlying mechanisms, and the pathology of glaucoma might lead to novel treatments and treatment of underlying diseases. In this review we present the latest research into glaucoma including the genetics and molecular basis of the disease.Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

基金：
This research was supported by Shaanxi Science and Technology Project (No. 2022SF-434), and Xi’an Science and Technology Project (No. 21YXYJ0044).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 1 区 医学
小类 | 2 区 生化与分子生物学 2 区 医学：研究与实验
最新[2025]版：
大类 | 2 区 医学
小类 | 2 区 生化与分子生物学 2 区 医学：研究与实验
JCR分区：
出版当年[2021]版：
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Q1 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版：
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Q1 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子： 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者：
第一作者机构： [1]Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated People's Hospital, Northwest University, Xi'an, 710004, Shaanxi Province, China.
通讯作者：
推荐引用方式(GB/T 7714)：
Wang Weiwei,Wang Huaizhou.Understanding the complex genetics and molecular mechanisms underlying glaucoma[J].MOLECULAR ASPECTS OF MEDICINE.2023,94:101220.doi:10.1016/j.mam.2023.101220.
APA：
Wang Weiwei&Wang Huaizhou.(2023).Understanding the complex genetics and molecular mechanisms underlying glaucoma.MOLECULAR ASPECTS OF MEDICINE,94,
MLA：
Wang Weiwei,et al."Understanding the complex genetics and molecular mechanisms underlying glaucoma".MOLECULAR ASPECTS OF MEDICINE 94.(2023):101220

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