It has long been suggested that a bidirectional impact exists between periodontitis and diabetes. Periodontitis may affect diabetes glycemic control, insulin resistance, and diabetic complications. Diabetes can worsen periodontitis by delaying wound healing and increasing the chance of infection. Extracellular vesicles (EVs) are heterogeneous particles of membrane-enclosed spherical structure secreted by eukaryotes and prokaryotes and play a key role in a variety of diseases. This review will introduce the biogenesis, release, and biological function of EVs from a microbial and host cell perspective, discuss the functional properties of EVs in the development of periodontitis and diabetes, and explore their role in the pathogenesis and clinical application of these two diseases. Their clinical implication and diagnostic value are also discussed.
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类|3 区医学
小类|3 区牙科与口腔外科3 区微生物学
最新[2025]版：
大类|3 区医学
小类|3 区牙科与口腔外科3 区微生物学
JCR分区：
出版当年[2022]版：
Q1DENTISTRY, ORAL SURGERY & MEDICINEQ2MICROBIOLOGY
最新[2023]版：
Q1DENTISTRY, ORAL SURGERY & MEDICINEQ3MICROBIOLOGY
第一作者机构：[1]Nova Southeastern Univ, Coll Dent Med, Dept Oral Sci & Translat Res, Ft Lauderdale, FL 33314 USA[2]Capital Med Univ, Beijing Tongren Hosp, Dept Stomatol, Beijing 100730, Peoples R China
通讯作者：
通讯机构：[1]Nova Southeastern Univ, Coll Dent Med, Dept Oral Sci & Translat Res, Ft Lauderdale, FL 33314 USA[2]Capital Med Univ, Beijing Tongren Hosp, Dept Stomatol, Beijing 100730, Peoples R China[*1]Department of Oral Science and Translation Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.[*2]Department of Stomatology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
推荐引用方式(GB/T 7714)：
Huang Shengyuan,Lin Jiang,Han Xiaozhe.Extracellular vesicles-Potential link between periodontal disease and diabetic complications[J].MOLECULAR ORAL MICROBIOLOGY.2024,39(4):225-239.doi:10.1111/omi.12449.
APA：
Huang, Shengyuan,Lin, Jiang&Han, Xiaozhe.(2024).Extracellular vesicles-Potential link between periodontal disease and diabetic complications.MOLECULAR ORAL MICROBIOLOGY,39,(4)
MLA：
Huang, Shengyuan,et al."Extracellular vesicles-Potential link between periodontal disease and diabetic complications".MOLECULAR ORAL MICROBIOLOGY 39..4(2024):225-239
