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Diabetes Pharmacotherapy and its effects on the Skeletal Muscle Energy Metabolism

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收录情况： ◇ SCIE

作者：

机构： [1]Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. [2]Department of Otolaryngology Head and Neck, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, China. [3]Department of Cadre Gastroenterology, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

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关键词： Type 2 diabetes mellitus skeletal muscle mitochondria metformin

摘要：

The disorders of skeletal muscle metabolism in patients with Type 2 diabetes mellitus (T2DM), such as mitochondrial defection and glucose transporters (GLUTs) translocation dysfunctions, are not uncommon. Therefore, when anti-diabetic drugs were used in various chronic diseases associated with hyperglycemia, the impact on skeletal muscle should not be ignored. However, current studies mainly focus on muscle mass rather than metabolism or functions. Anti-diabetic drugs might have a harmful or beneficial impact on skeletal muscle. In this review, we summarize the upto- date studies on the effects of anti-diabetic drugs and some natural compounds on skeletal muscle metabolism, focusing primarily on emerging data from pre-clinical to clinical studies. Given the extensive use of anti-diabetic drugs and the common sarcopenia, a better understanding of energy metabolism in skeletal muscle deserves attention in future studies.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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中科院(CAS)分区：

出版当年[2023]版中科院分区表Review为是的期刊

：

大类 | 3 区医学

小类 | 3 区药物化学

最新[2023]版

：

大类 | 3 区医学

小类 | 3 区药物化学

JCR分区：

出版当年[2022]版：

Q2 CHEMISTRY, MEDICINAL

最新[2023]版：

Q2 CHEMISTRY, MEDICINAL Q3 CHEMISTRY, MEDICINAL

影响因子： 3.3 最新[2023版] 3.7 最新五年平均 3.8 出版当年[2022版] 4.2 出版当年五年平均 3.737 出版前一年[2021版] 3.3 出版后一年[2023版]

第一作者：

第一作者机构： [1]Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

共同第一作者：

通讯作者：

通讯机构： [1]Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. [*1]Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

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Diabetes Pharmacotherapy and its effects on the Skeletal Muscle Energy Metabolism

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