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Preparing porcine lens to mimic human lens capsule

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机构： [1]Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi 030002, China. [2]School of Energy, Power and Mechanical Engineering, North China Electric Power University, 102206 Beijing, China. [3]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510060, China. [4]School of Mechanical Engineering & Automation, Beihang University, 10019 Beijing, China. [5]Beijing Institute of Ophthalmology, Beijing TongRen Eye Center, Beijing TongRen Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, 100730 Beijing, China.

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关键词： Anterior lens capsule Capsulorhexis Tear force Perforation force Animal model

摘要：

To develop a chemical method that makes porcine lens anterior capsule resemble human lens anterior capsule in tear force and perforating force.Beijing Tongren Hospital, Beijing, China.Experimental study.Porcine eyes were divided into groups, and reagents (0.9% physiological saline, 0.1% sodium hypochlorite, 0.3% sodium hypochlorite and 0.5% sodium hypochlorite) were injected into the anterior chamber respectively, recorded as groups A, B, C and D, respectively. A senior physician collected each group of anterior capsules after performing continuous circular capsulorhexis and assessing the anterior capsule's tearing and perforation forces.an additional group, which consisted of human lens anterior capsules taken in the operating room from cataract patients, recorded as group E. A tensile system was used to measure each sample's tensile force.A significant difference was found between group A and any other group in maximum tensile force and average tensile force both in transverse and longitudinal directions. No significant difference was found between any two groups from group B to group E. According to the surgeon's assessment, the tear force characteristic of the porcine lens anterior capsule treated with 0.1%, 0.3%, and 0.5% sodium hypochlorite solution was similar to that of the human lens anterior capsule.Porcine lens capsule treated using this method can be used for training of new surgeons. The porcine lens anterior capsule treated with 0.5% sodium hypochlorite, which results showed most resembled human lens anterior capsule, can be used for robotic training.Copyright © 2024 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.

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出版当年[2023]版：

大类 | 3 区医学

小类 | 2 区眼科学 3 区外科

最新[2023]版：

大类 | 3 区医学

小类 | 2 区眼科学 3 区外科

第一作者：

第一作者机构： [1]Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi 030002, China.

通讯作者：

通讯机构： [5]Beijing Institute of Ophthalmology, Beijing TongRen Eye Center, Beijing TongRen Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, 100730 Beijing, China. [*1]Beijing TongRen Hospital, Beijing, China,100730.

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