机构：[1]Research Asia Pacific, ALK, Guangzhou 510230, Guangdong, China[2]Department of Respiratory Medicine, the Affiliated Children's Hospital of Nanjing Medical University, Nanjing 210005, Jiangsu, China[3]State Key Laboratory of Respiratory Disease, the First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510230, Guangdong, China[4]ENT Department of Wuhan Union Hospital, Wuhan 430012, Hubei, China华中科技大学同济医学院附属协和医院[5]ENT Department of Beijing Tongren Hospital, Beijing 100730, China临床科室耳鼻咽喉-头颈外科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[6]Allergology Department of Shenyang 202 Hospital, Shenyang 110055, Liaoning, China[7]Asthmatic Children’s Immunotherapy Center of People’s Hospital of Hainan Province, Haikou 570311, Hainan, China[8]Respiratory Department, Children's Hospital of Chongqing Medical University, Chongqing 400014, China[9]Department of Medical Science and Occupational and Environmental Medicine, University Hospital, Uppsala University, Uppsala 75105, Sweden
Objective Chinese allergic subjects have high levels of sensitization to house dust mite (HDM) and other indoor allergens. This study quantifies common indoor allergen levels in Chinese households. Methods Dust samples were collected from nine cities. Major allergens Der p 1 and Der f 1 from Dermatophagoides pteronyssinus and D. farinae, and specific antigens of Blomia tropicalis, Tyrophagus putrescentiae, Acarus siro, and cockroach species Blattella germanica and Periplaneta americana were measured by ELISA. Results HDM allergens were found in dust samples from bedding in 95% of the Chinese households. The median levels varied from <0.006 to 9.2 mu g/g of dust, depending on the city. The percentages of households having HDM allergen levels associated with the risk of developing allergy sensitization and asthma were 65% and 25%, respectively. Specific antigens of the storage mite and cockroach were only found in samples from the southern and tropical regions of China. Levels of mite allergens were generally higher in samples from bedding compared to samples from the living room, even for storage mites, whereas levels of cockroach antigens were higher in the living room samples. Conclusion HDM allergens are present in bedding dust samples from most Chinese households. Cities in southern and central China have relatively high levels of HDM major allergens compared to cities in northern and western China. Antigens of storage mites and cockroaches are not as common as HDM allergens.
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2014]版：
大类|4 区环境科学与生态学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
最新[2025]版：
大类|4 区医学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
JCR分区：
出版当年[2013]版：
Q3ENVIRONMENTAL SCIENCESQ3PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
最新[2023]版：
Q2ENVIRONMENTAL SCIENCESQ2PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者机构：[1]Research Asia Pacific, ALK, Guangzhou 510230, Guangdong, China
通讯作者：
推荐引用方式(GB/T 7714)：
Zheng Yi Wu,Lai Xu Xin,Zhao De Yu,et al.Indoor Allergen Levels and Household Distributions in Nine Cities Across China[J].BIOMEDICAL AND ENVIRONMENTAL SCIENCES.2015,28(10):709-717.doi:10.3967/bes2015.101.
APA：
Zheng Yi Wu,Lai Xu Xin,Zhao De Yu,Zhang Chun Qing,Chen Jian Jun...&Spangfort, D. Michael.(2015).Indoor Allergen Levels and Household Distributions in Nine Cities Across China.BIOMEDICAL AND ENVIRONMENTAL SCIENCES,28,(10)
MLA：
Zheng Yi Wu,et al."Indoor Allergen Levels and Household Distributions in Nine Cities Across China".BIOMEDICAL AND ENVIRONMENTAL SCIENCES 28..10(2015):709-717
