机构：[1]Hongqiao International Institute of Medicine, Shanghai Tong Ren Hospital and Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China[2]School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China[3]Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People’s Republic of China[4]Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA
Background Many previous studies reported secular trend of lung cancer incidence and mortality, but little is known about the possible reasons for these trends. Methods Data were obtained from Shanghai Cancer Registry. Age-standardized rates were calculated and average annual percent changes (AAPCs) were evaluated by Joinpoint regression. Age, period, and birth cohort effects were assessed by age-period-cohort models. Results From 1973 to 2010, compared with long-time slowly increasing trend in women, male lung cancer incidence had significantly decreased between 2001 and 2009. After that lung cancer incidence rising sharply in women (AAPC = 14.13%, 95%CI: 2.68%-26.86%, P = .016) and similar rising trends without statistical significance in men (AAPC = 2.96, 95%CI: -2.47%-8.69%, P = .281) between 2010 and 2014. Age-period cohort model showed the different patterns of period effects for lung cancer incidence between men and women. The period effects for lung cancer incidence showed rising effect for women, whereas there was decline effect for lung cancer incidence for men. On the other hand, the model showed a significant period effect in both genders with a similar fashion in mortality, yielding steady falling trends during the entire study period. Conclusions The distinctive patterns of lung cancer incidence between men and women may be attributable to significant period effects, which reflected the changes in public health policies or diagnostic practices and highlighted the urgent of continued monitoring of gender-specific risk factors for lung cancer incidence.
基金：
Scientific Project of Shanghai Health
and Planning Commission, Grant/Award
Number: 20184Y0331; Three-year
Action Plan on Public Health, Phase Ⅳ,
Shanghai, China, Grant/Award Number:
15GWZK0802
第一作者机构：[1]Hongqiao International Institute of Medicine, Shanghai Tong Ren Hospital and Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China
共同第一作者：
通讯作者：
通讯机构：[1]Hongqiao International Institute of Medicine, Shanghai Tong Ren Hospital and Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China[2]School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China[3]Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People’s Republic of China[*1]Hongqiao International Institute of Medicine, Shanghai Tongren Hospital and Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, No. 227 South Chongqing Road, Shanghai, 200025, P. R. China[*2]Shanghai Center for Disease Prevention and Control, Shanghai 200336, China.
推荐引用方式(GB/T 7714)：
Xie Li,Qian Ying,Liu Yishan,et al.Distinctive lung cancer incidence trends among men and women attributable to the period effect in Shanghai: An analysis spanning 42 years[J].CANCER MEDICINE.2020,9(8):2930-2939.doi:10.1002/cam4.2917.
APA：
Xie, Li,Qian, Ying,Liu, Yishan,Li, Yixuan,Jia, Sinong...&Bao, Pingping.(2020).Distinctive lung cancer incidence trends among men and women attributable to the period effect in Shanghai: An analysis spanning 42 years.CANCER MEDICINE,9,(8)
MLA：
Xie, Li,et al."Distinctive lung cancer incidence trends among men and women attributable to the period effect in Shanghai: An analysis spanning 42 years".CANCER MEDICINE 9..8(2020):2930-2939
