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Effect of individualized therapy for AIDS patients with cytomegalovirus retinitis in intravitreal ganciclovir injections

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收录情况： ◇ SCIE

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机构： [1]Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China [2]Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing Tong Ren Hospital, Capital Medical University, Beijing 100730, China

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关键词： cytomegalovirus retinitis acquired immune deficiency syndrome ganciclovir intravitreal injection monotherapy

摘要：

The effect of intravitreal ganciclovir injection combined with intravenous infusion on acquired immune deficiency syndrome (AIDS) patients with cytomegalovirus retinitis (CMVR) was investigated. A total of 32 eyes in 23 AIDS patients diagnosed as CMVR from 2017 to 2018 were included in the retrospective study. All patients underwent induction therapy by using intravenous drip of the anti- cytomegalovirus (CMV) agent ganciclovir (5 mg/kg q12h) combined with intravitreal ganciclovir injection (3 mg/time, 2 times/wk). The visual acuity, fundus photographs, lesion location, and number of intravitreal injections were observed preoperatively and postoperatively. Totally 14 eyes were cured during induction therapy. The number of injections [4.13 (2 to 6)] in CMVR patients with peripherally fundus lesions were significantly lower than those with central lesions [4.89 (2 to 6)]. The individualized therapy of intravitreal ganciclovir injections for AIDS patients with CMVR can effectively reduce the numbers of intravitreal injections.

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出版当年[2018]版：

大类 | 4 区医学

小类 | 4 区眼科学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区眼科学

JCR分区：

出版当年[2017]版：

Q4 OPHTHALMOLOGY

最新[2023]版：

Q2 OPHTHALMOLOGY

影响因子： 1.9 最新[2023版] 1.8 最新五年平均 1.166 出版当年[2017版] 1.162 出版当年五年平均 1.177 出版前一年[2016版] 1.189 出版后一年[2018版]

第一作者：

第一作者机构： [1]Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China

通讯作者：

通讯机构： [2]Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing Tong Ren Hospital, Capital Medical University, Beijing 100730, China [*1]Beijing Tongren Eye Center, Beijing key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing Tong Ren Hospital, Capital Medical University, Beijing 100730, China.

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