高级检索
当前位置: 首页 > 详情页

Survival comparison of right and left side non-small cell lung cancer in stage I-IIIA patients: A Surveillance Epidemiology and End Results (SEER) analysis

文献详情

资源类型:
WOS体系:
Pubmed体系:

收录情况: ◇ SCIE

机构: [1]Peking Univ, Canc Hosp & Inst, Dept Thorac Med Oncol, Minist Educ Beijing,Key Lab Carcinogenesis & Tran, 52 Fucheng Rd, Beijing 100142, Peoples R China [2]Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing, Peoples R China [3]Capital Med Univ, Beijing Tongren Hosp, Key Lab Otolaryngol Head & Neck Surg, Minist Educ,Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China [4]Peking Univ, VIPII Gastrointestinal Canc Div, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Med Dept,Canc Hosp & Inst, Beijing, Peoples R China
出处:
ISSN:

关键词: Left side NSCLC right side SEER survival

摘要:
Background Primary tumors located in the right and left side have distinctive prognoses, but the details have not been fully identified in non-small cell lung cancer (NSCLC). This study investigated the impact of primary tumor side on long-term survival in NSCLC patients. Methods Data of 90 407 patients from the Surveillance, Epidemiology, and End Results (SEER) Program were analyzed. To avoid bias between groups, we used innovative propensity score matching (PSM) analysis. Results There was no significant distinction in overall survival (OS) between right (n = 53 496) and left (n = 36 911) side tumors (hazard ratio [HR] 0.993, 95% confidence interval [CI] 0.9756-1.011; P = 0.432). Left side was associated with superior five-year cancer-specific survival (CSS) compared to right side NSCLC (HR 0.977, 95% CI 0.9574-0.9969; P = 0.024). No significant difference was observed in OS (P = 0.689) or CSS (P = 0.288) after PSM analysis. In the 51 319 patients who underwent surgery, left side (n = 21 245) was associated with poor OS compared to right side (n = 30 074) NSCLC (HR 1.039, 95% CI 1.011-1.067; P = 0.006), while CSS was similar (HR 1.031, 95% CI 0.997-1.065; P = 0.069). In patients who underwent surgery, there was also no significant difference in OS (P = 0.986) or CSS (P = 0.979) after PSM analysis. Conclusion The prognosis between right and left side NSCLC in stage I-IIIA was similar regardless of whether patients underwent surgery. Primary tumor side cannot be considered a prognostic factor when choosing appropriate treatment.

语种:
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2018]版:
大类 | 4 区 医学
小类 | 4 区 肿瘤学 4 区 呼吸系统
最新[2023]版:
大类 | 3 区 医学
小类 | 4 区 肿瘤学 4 区 呼吸系统
JCR分区:
出版当年[2017]版:
Q3 RESPIRATORY SYSTEM Q3 ONCOLOGY
最新[2023]版:
Q2 RESPIRATORY SYSTEM Q3 ONCOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

第一作者:
第一作者机构: [1]Peking Univ, Canc Hosp & Inst, Dept Thorac Med Oncol, Minist Educ Beijing,Key Lab Carcinogenesis & Tran, 52 Fucheng Rd, Beijing 100142, Peoples R China
共同第一作者:
通讯作者:
通讯机构: [1]Peking Univ, Canc Hosp & Inst, Dept Thorac Med Oncol, Minist Educ Beijing,Key Lab Carcinogenesis & Tran, 52 Fucheng Rd, Beijing 100142, Peoples R China [*1]Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Thoracic Medical Oncology, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing 100142, China
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:21434 今日访问量:0 总访问量:1221 更新日期:2025-02-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学附属北京同仁医院 技术支持:重庆聚合科技有限公司 地址:北京市东城区东交民巷1号(100730)