Background: The lack of standardized treatment is problematic in laser surgery for laryngeal cancer, and may result in an increased recurrence rate. This study analyzed the prognosis of early laryngeal carcinoma after different types of cordectomy with laser surgery. Methods: A cohort of 818 patients with stage Tis or T1 primary early glottic squamous cell carcinoma treated with CO2 laser surgery was retrospectively analyzed. Results: Of the 818 patients, According to the Kaplan-Meier method, the rate of 5-year overall survival was 92.8%, and the rates for 5-year disease-specific survival and 5-year locoregional control were 96.9% and 91.3%, respectively. Among the T1 patients, type H cordectomy with laser surgery had a significant impact on the 5-year locoregional control rate, but no obvious impact on the 5-year overall survival rate. Conclusions: There must be sufficient depth and extent of excision in T1 patientsand in early carcinoma especially those with possible microinvasive carcinoma.
基金:
Hospitals Clinical Medicine Develpoment of Special Funding Support [XMLX201507]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81670946]; Training Programme Foundation for the Outstanding Young Talents of Beijing [2015000021469G227]
第一作者机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Otorhinolaryngol Head & Neck Surg, 1 DongJiaoMinXiang St, Beijing 100730, Peoples R China
共同第一作者:
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Otorhinolaryngol Head & Neck Surg, 1 DongJiaoMinXiang St, Beijing 100730, Peoples R China[*1]Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, 1, DongJiaoMinXiang Street, DongCheng District, Beijing 100730, PR China
推荐引用方式(GB/T 7714):
Ding Shuo,Huang Junwei,Huang Zhigang,et al.Variation in prognosis of early laryngeal carcinoma after different types of cordectomy with transoral laser microsurgery[J].ACTA OTO-LARYNGOLOGICA.2018,138(8):741-745.doi:10.1080/00016489.2018.1439592.
APA:
Ding, Shuo,Huang, Junwei,Huang, Zhigang,Xu, Hongbo,Guo, Wei&Zhang, Yang.(2018).Variation in prognosis of early laryngeal carcinoma after different types of cordectomy with transoral laser microsurgery.ACTA OTO-LARYNGOLOGICA,138,(8)
MLA:
Ding, Shuo,et al."Variation in prognosis of early laryngeal carcinoma after different types of cordectomy with transoral laser microsurgery".ACTA OTO-LARYNGOLOGICA 138..8(2018):741-745