详情页 - 首都医科大学附属北京同仁医院知识库

当前位置：首页 > 详情页

Fluid biopsy for circulating tumor cells in an occult ovarian cancer patient exhibiting bilateral supraclavicular lymph node metastases: A case report

3| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]Department of Otolaryngology‑Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology‑Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing 100730, P.R. China

出处：

DOI：

ISSN：

关键词： head and neck cancer unknown primary tumor supraclavicular lymph node metastases ovarian cancer circulating tumor cells

摘要：

Metastases to the supraclavicular region usually originate from the head and neck or from infraclavicular tumors. Ovarian primaries of supraclavicular metastases are extremely rare. The present study reports the case of a 60-year-old patient with a bilateral supraclavicular mass that was diagnosed as a poorly-differentiated squamous cell carcinoma of unknown primary, following a fine-needle aspiration biopsy (FNAB) and comprehensive clinical investigation. The analysis of a peripheral blood sample using the CellSearch system revealed the presence of circulating tumor cells (CTCs) that were positive for epithelial cell adhesion molecule (EpCAM) and cytokeratin (CK) expression. Since EpCAM is usually expressed in adenocarcinoma, an excisional biopsy of the right supraclavicular lymph node was performed. The patient was diagnosed with occult ovarian low-grade serous carcinoma by immunohistochemistry. To the best of our knowledge, this is the first report to demonstrate that CTCs may be detected in the peripheral blood of a patient with cancer of unknown primary (CUP) by using the CellSearch system. A literature review was performed to analyze the diagnostic procedures of CUP metastatic to the cervical lymph nodes and the clinical features of CTCs.

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2012]版：

大类 | 4 区医学

小类 | 4 区肿瘤学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区肿瘤学

JCR分区：

出版当年[2011]版：

Q4 ONCOLOGY

最新[2023]版：

Q3 ONCOLOGY

影响因子： 2.5 最新[2023版] 2.4 最新五年平均 0.108 出版当年[2011版] 0.108 出版当年五年平均 0 出版前一年[2010版] 0.237 出版后一年[2012版]

第一作者：

第一作者机构： [1]Department of Otolaryngology‑Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology‑Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing 100730, P.R. China

通讯作者：

通讯机构： [1]Department of Otolaryngology‑Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology‑Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing 100730, P.R. China [*1]Department of Otolaryngology‑Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology‑Head and Neck Surgery, Ministry of Education, Capital Medical University, No. 1 Dongjiaomin Xiang, Dongcheng, Beijing 100730, P.R. China

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Metabolomics of Oral/Head and Neck Cancer [2]Long noncoding RNA NR_027340 promotes head and neck cancer cell proliferation and glycolysis via PFKP [3]An Oxidative Stress Nanoamplifier to Enhance the Efficacy of Cisplatin in Head and Neck Cancer [4]Impact of pretreatment body mass index on the survival of head and neck cancer patients [5]LncRNA-SOX2-OT contributes to head and neck cancer cell proliferation by regulating DDIT4 [6]THERAPEUTIC EFFECTS OF A FUSOGENIC NEWCASTLE DISEASE VIRUS IN TREATING HEAD AND NECK CANCER [7]Heterogeneity of cancer-associated fibroblasts in head and neck squamous cell carcinoma: opportunities and challenges [8]Intratumoral Leptotrichia is a novel microbial marker for favorable clinical outcomes in head and neck cancer patients [9]GDFT on the Postoperative Outcome in Head and Neck Cancer Surgery [10]Gut microbiome's causal role in head and neck cancer: findings from mendelian randomization