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Lacunar infarction with leukoaraiosis may aggravate cognitive dysfunction

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收录情况： ◇ SCIE ◇ CSCD-C

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机构： [1]Department of Neurology,Lianyungang Second People's Hospital (Lianyungang Hospital of Bengbu Medical College)，Lianyungang 222023, Jiangsu Province，China [2]Department of Neurology,Beijing Tongren Hospita,Capital Medical University,Beijing 100730,China [3]Department of Neurology,Beijing Anzhen Hospital ,Capital Medical University,Beijing 100730 China [4]Neurophysiological Room．Lianyungang Second People's Hospital(Lianyungang Hospital of Bengbu Medical Colege)，Lianyungang 222023 Jiangsu Province,China [5]Department of Radiology,Lianyungang Second People's Hospital (Lianyungang Hospital of Bengbu Medical Colege)，Lianyungang 222023, Jiangsu Province，China

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关键词： lacunar infarction leukoaraiosis event-related potentials semi-quantitative analysis vascular cognitive impairment

摘要：

This study semi-quantitatively analyzed the effects of leukoaraiosis. Patients with moderate or severe lacunar infarction were found to exhibit low scores on the Montreal Cognitive Assessment Scale (F = 12.02, P = 0.000), and prolonged P300 Cz2.0 latency (F = 16.04, P = 0.000). Correlation analysis revealed that the occurrence of leukoaraiosis was negatively correlated with Montreal Cognitive Assessment scores (r = -0.416, P = 0.000), and positively correlated with P300 Cz2.0 latency (r = 0.538, P = 0.000). These findings indicate that leukoaraiosis aggravates cognitive impairment in patients with lacunar infarction, such that more severe leukoaraiosis is associated with more severe cognitive decline.

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出版当年[2010]版：

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最新[2025]版：

大类 | 2 区医学

小类 | 2 区细胞生物学 2 区神经科学

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出版当年[2009]版：

无

最新[2023]版：

Q1 NEUROSCIENCES Q2 CELL BIOLOGY

影响因子： 5.9 最新[2023版] 5.2 最新五年平均 0 出版当年[2009版] 0 出版当年五年平均 0 出版前一年[2008版] 0.18 出版后一年[2010版]

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第一作者机构： [1]Department of Neurology,Lianyungang Second People's Hospital (Lianyungang Hospital of Bengbu Medical College)，Lianyungang 222023, Jiangsu Province，China

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