机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Endocrinol, Beijing 100730, Peoples R China临床科室内分泌科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Ctr Dis Control & Prevent Changping Dist, Beijing, Peoples R China
Aim: To assess the prevalence of impaired fasting glucose among Chinese children and adolescents with prehypertension/hypertension (PHP/HP), overweight/obesity (OW/OB) or both in the general population. Methods: In total, 3409 children and adolescents among the age group of 10-18 years were enrolled. These subjects were then divided into four groups: OW/OB, PHP/HP, OW/OB + PHP/HP and a control group. Fasting plasma glucose (FPG) and lipid levels were measured in children with a body mass index >= 85th percentile and/or blood pressure >= 90th percentile and in 100 subjects randomly selected from the control group. The oral glucose tolerance test was performed in all the subjects with fasting glucose >= 5.6 mmol/L. Results: Eighty-one impaired fasting glucose subjects and one girl with type 2 diabetes were identified. The prevalence of impaired fasting glucose in PHP/HP (7.03%) was not significantly different from that in the OW/OB + PHP/HP group (8.59%), but was higher than that in the OW/OB group (3.31%). Conclusion: Although the American Diabetes Association does not recommend the FPG test for children and adolescents with PHP/HP, in this study, we found that children and adolescents with PHP/HP have a higher prevalence of impaired fasting glucose than those with OW/OB. Further validation of these findings is warranted and a type 2 diabetes screening protocol for Chinese children and adolescents needs to be established.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30671001]
第一作者机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Endocrinol, Beijing 100730, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Zhao Lei,Ma Ya-Hong,Xu Jian-Xin,et al.High prevalence of impaired fasting glucose in Chinese children and adolescents with prehypertension/hypertension[J].ACTA PAEDIATRICA.2009,98(10):1641-1645.doi:10.1111/j.1651-2227.2009.01424.x.
APA:
Zhao, Lei,Ma, Ya-Hong,Xu, Jian-Xin,Li, Shu-Bo&Yang, Jin-Kui.(2009).High prevalence of impaired fasting glucose in Chinese children and adolescents with prehypertension/hypertension.ACTA PAEDIATRICA,98,(10)
MLA:
Zhao, Lei,et al."High prevalence of impaired fasting glucose in Chinese children and adolescents with prehypertension/hypertension".ACTA PAEDIATRICA 98..10(2009):1641-1645