Introduction Conductive Keratoplasty (CK) induce refractive change of comea by peripheral deformation[1]. The pred ictability of CK is still unsatisfactory, partly due to wound-heating response and refractive regression [2]. Because the same, Mery operation was performed on comeas of different curvature [3 4, we infer that different curvature of comea may be one of the reasons for diverse surgery results. In this paper, the effect of different curvature of comea on corrected power of conductive keratoplasty was evaluated. Methods Mathematical analysis was done on the assumption that front surface of deformation zone of comea is spherical before and after surgery, back surface of comea is stable before and after surgery. Results After surgical deformation, relative change of refractive power of front surface of comea Delta phi/phi =(R-r)/r=Delta R/h, where R is curvature radius of front surface of comea before surgery, r is that after surgery, Delta R is the deformation of comea at location of surgical operation, h is the difference of height between apex of cornea and location of surgical operation. Absolute change of refractive power of comea Delta phi approximate to-2(n-1)Delta R/L-2, where n is refractive index of comea, L is the distance from the location of surgical operation to the axis of comea. Calculation by the above formula with operation values of actual surgery shows that the absolute theoretical errors will be less than 0.1 diopter. Thus, refractive power change of cornea induced by peripheral deformation has linearity relationship with deformation and change rapidly with surgery location, but it is almost stable with different curvature of comea. Conclusion Both deformation and surgery location are parameters related to surgery response, surgery regression and surgery operation. Hence, different surgery response, surgery regression and unsatisfactory precision of surgery operation are main causes for unsatisfactory predictability of such surgery. New work to be presented Theoretical analysis shows that different curvature of comea has little effect on corrected power of conductive keratoplasty.