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Glaucoma neurodegeneration and myopia

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收录情况： ◇ SCIE

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机构： [1]Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karis-University, Mannheim, Germany [2]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China [3]Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Kutzerufer 1, 68167 Mannheim, Germany.

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关键词： High myopia Myopia Glaucoma Glaucomatous optic neuropathy Optic nerve head Optic disc Parapapillary gamma zone Parapapillary delta zone Lamina cribrosa

摘要：

Beyond a cut-off value of approximately 26.5mm, the prevalence of glaucomatous or glaucoma-like optic neuropathy (GON) increases with longer axial length. In a hospital-based study, the prevalence of GON was 42% in eyes with an axial length of >= 30mm. Myopia-associated histological changes potentially associated with the increased GON prevalence are an elongation and thinning of the lamina cribrosa and peripapillary scleral flange. Correspondingly, clinical parameters associated with an increased GON prevalence were an enlargement of the optic disc and parapapillary delta zone. In addition to GON, a non-glaucomatous optic nerve damage can occur in highly myopic eyes, potentially due to a parapapillary gamma zone-associated lengthening of the retinal nerve fibers in the papillo-macular bundle. Clinically, GON and non-glaucomatous optic neuropathy should be ruled out in any highly myopic eye, in particular in those with a large optic disc, gamma zone and delta zone.

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出版当年[2019]版中科院分区表Review为是的期刊

：

大类 | 3 区医学

小类 | 4 区神经科学

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出版当年[2018]版：

Q2 NEUROSCIENCES

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影响因子： 0 最新[2023版] 0 最新五年平均 2.961 出版当年[2018版] 2.996 出版当年五年平均 3.174 出版前一年[2017版] 1.746 出版后一年[2019版]

第一作者：

第一作者机构： [1]Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karis-University, Mannheim, Germany [3]Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Kutzerufer 1, 68167 Mannheim, Germany.

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通讯作者：

通讯机构： [1]Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karis-University, Mannheim, Germany [3]Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Kutzerufer 1, 68167 Mannheim, Germany.

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