机构：[1]Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China临床科室耳鼻咽喉-头颈外科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Beijing Laboratoryof Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China研究所耳鼻咽喉科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院[3]Research Unit of Diagnosisand Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China[4]Department of Otorhinolaryngology & ClinicalAllergy Center, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China江苏省人民医院[5]International Centre for Allergy Research, NanjingMedical University, Nanjing, China[6]Department of Otolaryngology Head Neck Surgery, Eye & ENT Hospital of Fudan University, Shanghai,China[7]Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science andTechnology, Wuhan, China华中科技大学同济医学院附属同济医院[8]Otorhinolaryngology Hospital, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China中山大学附属第一医院[9]Departmentof Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China[10]Department of Otorhinolaryngology-Head andNeck Surgery, Department of Allergy, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China中山大学附属第三医院[11]Research Units of New Technologiesof Endoscopic Surgery in Skull Base Tumor, Chinese Academy of Medical Sciences, Shanghai, China[12]Department of Otorhinolaryngology-Headand Neck Surgery, Second Hospital of Shanxi Medical University, Taiyuan, China[13]Department of Otorhinolaryngology Head and Neck Surgery,China-Japan Union Hospital of Jilin University, Changchun, China吉林大学中日联谊医院[14]Department of Otolaryngology, the Seventh Affiliated Hospital, Sun Yat-senUniversity, Shenzhen, China深圳市康宁医院深圳医学信息中心中国医学科学院阜外医院深圳医院[15]Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China临床科室变态反应科首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and safety. However, no consensus or guideline has been formulated on the use of steroid transnasal nebulization in treating CRS. The consensus is achieved through literature review and exchange of Chinese experts in Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA). This document covers the development, equipment, pharmacological mechanism, and evidence-based efficacy and safety, as well as the special concern of the application of steroid transnasal nebulization during the coronavirus disease (COVID-19) pandemic. The expert consensus clarifies the application of steroid transnasal nebulization in treating CRS and common comorbidities during the perioperative and postoperative periods.
基金：
national natural science foundation of ChinaNational Natural Science Foundation of China (NSFC) [81630023, 81970850, 81870698, 82025010]; National Key R & D Program of China [2018YFC0116800]; CAMS Innovation Fund for Medical Sciences (CIFMS) [2019-I2M-5-022, 2021-I2M-CT-B-098]; Program for Changjiang Scholars and Innovative Research TeamProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT13082]; Beijing Municipal Science and Technology Project [Z181100001618002]
第一作者机构：[1]Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China[2]Beijing Laboratoryof Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China[3]Research Unit of Diagnosisand Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China[2]Beijing Laboratoryof Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China[3]Research Unit of Diagnosisand Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China[15]Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China[*1]Beijing Tongren Hospital, No. 1, Dongjiaominxiang, Dongcheng District, Beijing 100005, China
推荐引用方式(GB/T 7714)：
Chengshuo Wang,Lei Cheng,Huabin Li,et al.Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021[J].JOURNAL OF THORACIC DISEASE.2021,13(11):6217-6229.doi:10.21037/jtd-21-1142.
APA：
Chengshuo Wang,Lei Cheng,Huabin Li,Zheng Liu,Hongfei Lou...&Luo Zhang.(2021).Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021.JOURNAL OF THORACIC DISEASE,13,(11)
MLA：
Chengshuo Wang,et al."Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021".JOURNAL OF THORACIC DISEASE 13..11(2021):6217-6229
