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Ruthenium-106 plaque brachytherapy for the treatment of diffuse choroidal hemangioma in Sturge-Weber syndrome.

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机构: [1]Department of Ophthalmology & Clinical Center of Optometry, Peking University People’s Hospital, Beijing 100044, China [2]Eye Diseases and Optometry Institute Peking University People’s Hospital, Beijing 100044, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China [4]College of Optometry, Peking University Health Science Center, Beijing 100191, China
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关键词: diffuse choroidal hemangioma Sturge-Weber syndrome plaque brachytherapy

摘要:
To evaluate the efficacy of ruthenium-106 plaque brachytherapy for the treatment of diffuse choroidal hemangioma (DCH) in Sturge-Weber syndrome (SWS).A total of 8 patients with DCH in SWS managed with plaque brachytherapy were retrospectively included. Patients were treated with ruthenium-106 plaque therapy (median apex dose: 83 Gy) at the thickest tumor region. On follow-up, we recorded the tumor thickness, the best-corrected visual acuity (BCVA), subretinal fluid (SRF) status, and complications following treatment.At a median follow-up of 43mo, tumor regression was observed in all cases, with a complete resolution of SRF and reduction in tumor-thickness. No radiation complications were recorded during the follow up time.Ruthenium-106 plaque therapy to the thickest portion of the tumor seems to be a useful treatment in patients with DCH in SWS.International Journal of Ophthalmology Press.

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出版当年[2019]版:
大类 | 3 区 医学
小类 | 3 区 眼科学
最新[2025]版:
大类 | 4 区 医学
小类 | 3 区 眼科学
第一作者:
第一作者机构: [1]Department of Ophthalmology & Clinical Center of Optometry, Peking University People’s Hospital, Beijing 100044, China [2]Eye Diseases and Optometry Institute Peking University People’s Hospital, Beijing 100044, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China [4]College of Optometry, Peking University Health Science Center, Beijing 100191, China
通讯作者:
通讯机构: [1]Department of Ophthalmology & Clinical Center of Optometry, Peking University People’s Hospital, Beijing 100044, China [2]Eye Diseases and Optometry Institute Peking University People’s Hospital, Beijing 100044, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China [4]College of Optometry, Peking University Health Science Center, Beijing 100191, China [*1]Department of Ophthalmology, Peking University People’s Hospital, No.11 Xizhimen South Avenue, Xicheng District, Beijing 100044, China.
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