Preoperative systemic and local inflammation are independent risk factors for difficult laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage
Background: Laparoscopic cholecystectomy (LC) is required for acute cholecystitis patient with percutaneous transhepatic gallbladder drainage (PTGBD). However, it's unknown how to distinguishing the surgical difficulty for these patients. Methods: Data of patients who underwent LC after PTGBD between 2016 and 2022 were collected. Patients were categorized into difficult and non-difficult operations based on operative time, blood loss, and surgical conversion. Performance of prediction model was evaluated by ROC, calibration, and decision curves. Results: A total of 127 patients were analyzed, including 91 in non-difficult operation group and 36 in difficult operation group. Elevated CRP (P = 0.011), pericholecystic effusion (P < 0.001), and contact with stomach or duodenal (P = 0.015) were independent risk factors for difficult LC after PTGBD. A nomogram was developed according to these risk factors, and was well-calibrated and good at distinguishing difficult LC after PTGBD. Conclusion: Preoperative elevated systemic and local inflammation indictors are predictors for difficult LC after PTGBD.
基金：
Natural Science Foundation of the Science and Technology Commission of Shanghai Municipality [18ZR1429600]
第一作者机构：[1]Shanghai Jiao Tong Univ, Tongren Hosp, Dept Cardiovasc Surg, Sch Med, Shanghai, Peoples R China[2]Tongji Univ, Shanghai Peoples Hosp 10, Dept Gen Surg, Sch Med, Shanghai, Peoples R China
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推荐引用方式(GB/T 7714)：
Wei Hai-Hong,Wang Yu-Xiang,Xu Bin,et al.Preoperative systemic and local inflammation are independent risk factors for difficult laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage[J].HELIYON.2024,10(16):doi:10.1016/j.heliyon.2024.e36081.
APA：
Wei, Hai-Hong,Wang, Yu-Xiang,Xu, Bin&Zhang, Yong-Gui.(2024).Preoperative systemic and local inflammation are independent risk factors for difficult laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage.HELIYON,10,(16)
MLA：
Wei, Hai-Hong,et al."Preoperative systemic and local inflammation are independent risk factors for difficult laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage".HELIYON 10..16(2024)
