机构：[1]Department of Respiratory and Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China,首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Department of Internal Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China华中科技大学同济医学院附属协和医院[3]Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China,临床科室重症医学科-中心ICU首都医科大学附属北京同仁医院首都医科大学附属同仁医院[4]Department of Otolaryngology and Head Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China,临床科室耳鼻咽喉-头颈外科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[5]Department of Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Objective: The recent outbreak of Novel Coronavirus Disease (COVID-19) is reminiscent of the SARS outbreak in 2003. We aim to compare the severity and mortality between male and female patients with COVID-19 or SARS. Study Design and Setting: We extracted the data from: (1) a case series of 43 hospitalized patients we treated, (2) a public data set of the first 37 cases of patients who died of COVID-19 and 1,019 patients who survived in China, and (3) data of 524 patients with SARS, including 139 deaths, from Beijing in early 2003. Results: Older age and a high number of comorbidities were associated with higher severity and mortality in patients with both COVID-19 and SARS. Age was comparable between men and women in all data sets. In the case series, however, men's cases tended to be more serious than women's (P = 0.035). In the public data set, the number of men who died from COVID-19 is 2.4 times that of women (70.3 vs. 29.7%, P = 0.016). In SARS patients, the gender role in mortality was also observed. The percentage of males were higher in the deceased group than in the survived group (P = 0.015). Conclusion: While men and women have the same prevalence, men with COVID-19 are more at risk for worse outcomes and death, independent of age.
基金：
National Key R&D Program of China [2017YFC0909600]; High-level Talent Training Foundation of Beijing Health System [2014-3-011]; Beijing Talent Training Foundation [2009D003003000002]
第一作者机构：[1]Department of Respiratory and Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China,[2]Department of Internal Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
通讯作者：
推荐引用方式(GB/T 7714)：
Jin Jian-Min,Bai Peng,He Wei,et al.Gender Differences in Patients With COVID-19: Focus on Severity and Mortality[J].FRONTIERS IN PUBLIC HEALTH.2020,8:doi:10.3389/fpubh.2020.00152.
APA：
Jin, Jian-Min,Bai, Peng,He, Wei,Wu, Fei,Liu, Xiao-Fang...&Yang, Jin-Kui.(2020).Gender Differences in Patients With COVID-19: Focus on Severity and Mortality.FRONTIERS IN PUBLIC HEALTH,8,
MLA：
Jin, Jian-Min,et al."Gender Differences in Patients With COVID-19: Focus on Severity and Mortality".FRONTIERS IN PUBLIC HEALTH 8.(2020)
