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Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology

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机构: [1]Univ Hosp Leuven, Clin Div Otorhinolaryngol Head & Neck Surg, Leuven, Belgium [2]Katholieke Univ Leuven, Lab Clin Immunol, Dept Microbiol & Immunol, Leuven, Belgium [3]Ctr Rhinol & Allergol, Wiesbaden, Germany [4]Univ Eskisehir Osmangazi, Dept Otorhinolaryngol Head & Neck Surg, Eskisehir, Turkey [5]Transylvania Univ, Dept Allergy & Clin Immunol, Brasov, Romania [6]Univ Zurich, Swiss Inst Allergy & Asthma Res, Christine Kuhne Ctr Allergy Res & Educ, Davos, Switzerland [7]Ghent Univ Hosp, Upper Airway Res Lab, Ghent, Belgium [8]Univ Hosp Montpellier, Hop Arnaud Villeneuve, Montpellier, France [9]Clin Univ St Luc, Serv ORL, Brussels, Belgium [10]UCL, IREC, Pole Pneumol, ORL & Dermatol, Brussels, Belgium [11]Univ Hosp Sestre Milosrdnice, Dept Otorhinolaryngol & Head & Neck Surg, Zagreb, Croatia [12]Univ Oradea, ENT Dept, Fac Med, Oradea, Romania [13]Univ Cologne, Inst Med Stat Informat & Epidemiol, Fac Med, Cologne, Germany [14]Hosp Clin Barcelona, Unitat Rinol & Clin Olfacte, Serv Otorinolaringol, Barcelona, Catalonia, Spain [15]Kirikkale Univ, ENT Dept, Fac Med, Kirikkale, Turkey [16]Univ Padua, Referral Ctr Food Allergy Diag & Treatment Veneto, Dept Mother & Child Hlth, Padua, Italy [17]Univ Athens, Allergy Dept, Pediat Clin 2, Athens, Greece [18]Nippon Med Sch, Tokyo, Japan [19]Carlos Haya Hosp, Allergy Serv, Malaga, Spain [20]London Allergyol & Immunol Ctr, London, England [21]Temple Univ, Dept Otorhinolaryngol Head & Neck Surg, Philadelphia, PA 19122 USA [22]Capital Med Univ, Dept Otolaryngol Head & Neck Surg, Beijing Tongren Hosp, Beijing, Peoples R China [23]AMC, Dept Otorhinolaryngol Head Neck Surg, Amsterdam, Netherlands [24]Univ Manchestter, Manchester, Lancs, England
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关键词: classification nonallergic rhinitis rhinitis treatment

摘要:
This EAACI position paper aims at providing a state-of-the-art overview on nonallergic rhinitis (NAR). A significant number of patients suffering from persistent rhinitis are defined as nonallergic noninfectious rhinitis (NANIR) patients, often denominated in short as having NAR. NAR is defined as a symptomatic inflammation of the nasal mucosa with the presence of a minimum of two nasal symptoms such as nasal obstruction, rhinorrhea, sneezing, and/or itchy nose, without clinical evidence of endonasal infection and without systemic signs of sensitization to inhalant allergens. Symptoms of NAR may have a wide range of severity and be either continuously present and/or induced by exposure to unspecific triggers, also called nasal hyperresponsiveness (NHR). NHR represents a clinical feature of both AR and NAR patients. NAR involves different subgroups: drug-induced rhinitis, (nonallergic) occupational rhinitis, hormonal rhinitis (including pregnancy rhinitis), gustatory rhinitis, senile rhinitis, and idiopathic rhinitis (IR). NAR should be distinguished from those rhinitis patients with an allergic reaction confined to the nasal mucosa, also called entopy or local allergic rhinitis (LAR). We here provide an overview of the current consensus on phenotypes of NAR, recommendations for diagnosis, a treatment algorithm, and defining the unmet needs in this neglected area of research.

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出版当年[2016]版:
大类 | 1 区 医学
小类 | 2 区 过敏 2 区 免疫学
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 免疫学 2 区 过敏
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出版当年[2015]版:
Q1 ALLERGY Q1 IMMUNOLOGY
最新[2023]版:
Q1 IMMUNOLOGY Q1 ALLERGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

第一作者:
第一作者机构: [1]Univ Hosp Leuven, Clin Div Otorhinolaryngol Head & Neck Surg, Leuven, Belgium [2]Katholieke Univ Leuven, Lab Clin Immunol, Dept Microbiol & Immunol, Leuven, Belgium [*1]Univ Hosp Leuven, Dept Otorhinolaryngol Head & Neck Surg, Leuven, Belgium
通讯作者:
通讯机构: [1]Univ Hosp Leuven, Clin Div Otorhinolaryngol Head & Neck Surg, Leuven, Belgium [2]Katholieke Univ Leuven, Lab Clin Immunol, Dept Microbiol & Immunol, Leuven, Belgium [*1]Univ Hosp Leuven, Dept Otorhinolaryngol Head & Neck Surg, Leuven, Belgium
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