机构：[1]School of Public Health, Shanghai Jiaotong University, Shanghai 200025, PR China[2]Shanghai Children's Medical Center, Shanghai 200127, PR China[3]School of Environmental Science & Engineering, Shanghai Jiaotong University, Shanghai 200240, PR China[4]Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine (or Faculty of Public Health), Shanghai Jiao Tong University School of Medicine, PR China[5]MOE and Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
Halogenated persistent organic pollutants (Hal-POPs) are significant contaminants in the indoor environment that are related to many human diseases. Ingestion of indoor dust is considered the major pathway of Hal-POP exposures, especially for children aged 3-6 years. Alongside a retrospective study on the associations between typical Hal-POP exposure and childhood asthma in Shanghai, indoor dust samples from asthmatic and non-asthmatic children's homes (n = 60, each) were collected. Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) were measured by GC MS. BDE-209, PCB -8 and p,p'-DDE were the predominant components in each chemical category. The concentrations of most Hal-POPs were significantly higher in the asthmatic families. The associations between Hal-POP exposure and asthma occurrence were examined by calculating the odds ratios (ORs) using a logistic regression model. A positive association was found between p,p'-DDE in indoor dust and childhood asthma (OR = 1.825, 95%Cl: 1.004, 3.317; p = 0.048). The average daily doses of Hal-POP intake were calculated using the method provided by the USEPA. Non carcinogenic health risks were preliminarily assessed. Our study indicated that exposure to p,p'-DDE via indoor dust may contribute to childhood asthma occurrence. Non-carcinogenic health risks were not found with the intake of Hal-POPs via the ingestion of indoor dust. (C) 2015 Elsevier Ltd. All rights reserved.
基金：
Innovation Program of Shanghai Municipal Education CommissionInnovation Program of Shanghai Municipal Education Commission [14YZ043]
第一作者机构：[1]School of Public Health, Shanghai Jiaotong University, Shanghai 200025, PR China
通讯作者：
通讯机构：[1]School of Public Health, Shanghai Jiaotong University, Shanghai 200025, PR China[4]Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine (or Faculty of Public Health), Shanghai Jiao Tong University School of Medicine, PR China[5]MOE and Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China[*1]School of Public Health, Shanghai Jiaotong University, Shanghai 200025, PR China
推荐引用方式(GB/T 7714)：
Meng Ge,Nie Zhiqing,Feng Yan,et al.Typical halogenated persistent organic pollutants in indoor dust and the associations with childhood asthma in Shanghai, China[J].ENVIRONMENTAL POLLUTION.2016,211:389-398.doi:10.1016/j.envpol.2015.12.006.
APA：
Meng, Ge,Nie, Zhiqing,Feng, Yan,Wu, Xiaomeng,Yin, Yong&Wang, Yan.(2016).Typical halogenated persistent organic pollutants in indoor dust and the associations with childhood asthma in Shanghai, China.ENVIRONMENTAL POLLUTION,211,
MLA：
Meng, Ge,et al."Typical halogenated persistent organic pollutants in indoor dust and the associations with childhood asthma in Shanghai, China".ENVIRONMENTAL POLLUTION 211.(2016):389-398
