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Prevalence of optic disc drusen in an adult Chinese population: the Beijing Eye Study

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机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital MedicalUniversity, Beijing, China [2]Department of Ophthalmology, Faculty of Clinical Medicine Mannheim,University of Heidelberg, Mannheim, Germany

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关键词： axoplasmic flow oligodendrocytes optic disc drusen optic nerve pseudopapilloedema retina visual field loss

摘要：

This study aimed to determine the prevalence of optic disc drusen and their associations with ocular and general parameters. The Beijing Eye Study included 4439 of 5324 subjects invited to participate (response rate 83.4%). All subjects were aged >= 40 years. The present investigation involved 8594 (96.8%) eyes of 4324 (97.4%) subjects from whom readable fundus photographs of at least one eye were available. The main outcome parameter was the presence of optic disc drusen defined as round, whitish bodies. Optic disc drusen were detected in nine (0.1 +/- 0.05%) eyes of eight subjects (five women). The prevalence rate was 0.2 +/- 0.07% (95% confidence interval 0.07-0.33%) per subject. Optic disc drusen were significantly associated with small optic discs (p < 0.001). They were not statistically associated with age (p = 0.90), gender (p = 0.73), intraocular pressure (p = 0.97), refractive error (p = 0.71), visual field defects (p = 0.47) or corrected visual acuity (p = 0.84). Optic disc drusen are present in about two in 1000 adult Chinese people in Northern China. The main associated factor is a small optic disc.

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出版当年[2008]版：

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最新[2025]版：

大类 | 3 区医学

小类 | 2 区眼科学

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出版当年[2007]版：

无

最新[2023]版：

Q1 OPHTHALMOLOGY

影响因子： 3 最新[2023版] 3.3 最新五年平均 0 出版当年[2007版] 0 出版当年五年平均 0 出版前一年[2006版] 2.138 出版后一年[2008版]

第一作者：

第一作者机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital MedicalUniversity, Beijing, China

通讯作者：

通讯机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital MedicalUniversity, Beijing, China [2]Department of Ophthalmology, Faculty of Clinical Medicine Mannheim,University of Heidelberg, Mannheim, Germany [*1]Universita¨ts-AugenklinikTheodor-Kutzer-Ufer 1)368167 MannheimGermany

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