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Assessment of the specificity of corvis biomechanical index-laser vision correction (CBI-LVC) in stable corneas after phototherapeutic keratectomy

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机构: [1]Humanitas San Pio X Hospital, Via Francesco Nava 31, Milan, Italy [2]The School of Engineering, University of Liverpool, Liverpool, UK [3]Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Milan, Italy [4]Department of Ophthalmology, The Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro, Brazil [5]Department of Ophthalmology, The Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil [6]Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100083, China [7]NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK [8]Humanitas Clinical and Research Center–IRCCS, Via Manzoni 56, 20089 Rozzano, Mi, Italy
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关键词: Corneal Biomechanics PTK Ectasia Keratocon

摘要:
The Corvis Biomechanical Index-Laser Vision Correction (CBI-LVC) is a biomechanical index to detect ectasia in post-refractive surgery patients (PRK, LASIK, SMILE). This study aims to evaluate the distribution of the CBI-LVC in stable patients who underwent Phototherapeutic Keratectomy (PTK) compared to PRK patients.Patients who underwent PRK and PTK performed between 2000 and 2018 in Humanitas Research Hospital, Rozzano, Milan, Italy and remained stable for at least four years post-surgery were included. All eyes were examined with the Corvis ST (Oculus, Germany), whose output allows the calculation of the CBI-LVC. The distribution and specificity of the CBI-LVC in the two populations were estimated using a Wilcoxon Mann-Whitney test and compared.175 eyes of 148 patients were included (85 eyes of 50 PTK patients and 90 eyes of 90 PRK patients). The distribution of CBI-LVC in the two groups showed a minor difference, with a median value in PRK patients of 0.000 (95% CI 0.000; 0.002) and 0.008 (95% CI 0.000; 0.037) in PTK patients (Mann-Whitney U test p = 0.023). The statistical analysis showed that the CBI-LVC provided a specificity of 92.22% in the PRK group, while in the PTK group it was 82.35%. Nevertheless, this difference was not statistically significant (Chi-squared test with Yates, p = 0.080).CBI-LVC provided similar specificity in stable PTK patients compared to those who underwent PRK. These results suggest that the CBI-LVC could be a useful tool to aid corneal surgeons in managing PTK patients.© 2023. The Author(s), under exclusive licence to Springer Nature B.V.

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出版当年[2022]版:
大类 | 4 区 医学
小类 | 4 区 眼科学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 眼科学
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第一作者机构: [1]Humanitas San Pio X Hospital, Via Francesco Nava 31, Milan, Italy [2]The School of Engineering, University of Liverpool, Liverpool, UK
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通讯机构: [3]Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Milan, Italy [8]Humanitas Clinical and Research Center–IRCCS, Via Manzoni 56, 20089 Rozzano, Mi, Italy
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